Ultrasound-mediated, uranyl nitrate hexahydrate-catalyzed synthesis of 1,4-dihydropyridines under mild conditions

被引：8

作者：

Reddy, B. Palakshi ^{[1
]}

Sarveswari, S. ^{[1
]}

Vijayakumar, V. ^{[1
]}

机构：

[1] VIT Univ, Ctr Organ & Med Chem, Vellore 632014, Tamil Nadu, India

来源：

RESEARCH ON CHEMICAL INTERMEDIATES | 2015年 / 41卷 / 09期

关键词：

1,4-DHPs; Uranyl nitrate hexahydrate; Ultrasound irradiation; SOLVENT-FREE CONDITIONS; ONE-POT SYNTHESIS; SUBSTITUTED 2,5-DIOXO-1,2,3,4,5,6,7,8-OCTAHYDROQUINOLINES; HANTZSCH 1,4-DIHYDROPYRIDINES; IONIC LIQUID; DERIVATIVES; EFFICIENT; ANALOGS; 3,5-DIACETYL-1,4-DIHYDROPYRIDINES; PHOTOCHEMISTRY;

D O I：

10.1007/s11164-014-1784-5

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Synthesis of 1,4-dihydropyridines by three-component condensation reaction of aldehyde, 1,3-dicarbonyl compounds, and ammonium acetate have been found to be efficiently catalyzed by uranyl nitrate hexahydrate [UO2(NO3)(2)center dot 6H(2)O] at room temperature under ultrasound irradiation. This novel synthetic method offers the advantages of high yields, short reaction times, simplicity, and easy workup compared to the conventional methods reported in the literature.

引用

页码：6877 / 6883

页数：7

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