A modified automated high-throughput mycobacterial interspersed repetitive unit method for genotyping Mycobacterium tuberculosis

被引:15
作者
Chin, PJ [1 ]
Jou, RW [1 ]
机构
[1] Dept Hlth, Ctr Dis Control, Reference Lab Mycobacteriol, Taipei 115, Taiwan
关键词
Mycobacterium tuberculosis; repetitive unit; high-throughput genotyping;
D O I
10.1016/j.diagmicrobio.2005.05.013
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
A total of 502 isolates of Mycobacterium tuberculosis collected in Taiwan were genotyped using a modified and high-throughput typing system involving mycobacterial interspersed repetitive units. The Hunter-Gaston discriminatory index improved significantly to 0.972 with the modified 15-locus scheme, including ETR-A, ETR-B, and ETR-C, compared with 0.951 for the previously reported 12-locus design. (c) 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码:325 / 327
页数:3
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