Esophageal tuberculosis presenting as a submucosal tumor

Introduction: Esophageal involvement by tuberculosis is quite rare and the diagnosis can be difficult. In this article, we report a case of esophageal tuberculosis in a patient who at first presented as a submucosal tumor. Methods: The diagnostic process of the patient was described in this article. And an online search was performed in PubMed and Web of Science databases for articles describing the information of esophageal tuberculosis. Results and Conclusions: Most esophageal tuberculosis cases are secondary to the adjacent sites. Endoscopic features mainly include two types, ulcers and extrinsic bulge, which may be two stages of lesion. EUS combine biopsy can help diagnosis. In cases which are difficult to diagnose, the endoscopic mucosal resection combined with PCR test of the tissue can increase the positive rate.