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Advances in the Orthopedic Management of Osteogenesis Imperfecta
被引:11
|作者:
Laron, Dominique
[1
]
Pandya, Nirav K.
[1
]
机构:
[1] Univ Calif San Francisco, Childrens Hosp & Res Ctr Oakland, Dept Orthoped Surg, Oakland, CA 94609 USA
关键词:
Osteogenesis imperfecta;
Advances;
Medical;
Surgical;
Orthopedic;
Bisphosphonates;
Intramedullary fixation;
SOFIELD-MILLAR OPERATION;
BISPHOSPHONATE TREATMENT;
INTRAMEDULLARY RODS;
PRENATAL-DIAGNOSIS;
I COLLAGEN;
LOWER-LIMB;
CHILDREN;
MUTATIONS;
PAMIDRONATE;
COMPLICATIONS;
D O I:
10.1016/j.ocl.2013.06.010
中图分类号:
R826.8 [整形外科学];
R782.2 [口腔颌面部整形外科学];
R726.2 [小儿整形外科学];
R62 [整形外科学(修复外科学)];
学科分类号:
摘要:
The long-established study of osteogenesis imperfecta (OI) has opened a realm of scientific research surrounding connective tissue disorders. Over the past decade alone there have been vast advancements in the understanding of the underlying genetic variations of this disease, pharmacologic treatments, and the technological and surgical options for fracture deformity. It is important to appreciate the progressive nature of the advances concerning OI. This article aims to synthesize the expanding evolution of the field surrounding OI over the past decade.
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页码:565 / +
页数:10
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