Long-acting glucagon-like peptide-1 receptor agonist-status December 2018

被引:17
作者
Holst, Jens Juul [1 ,2 ]
机构
[1] Univ Copenhagen, Panum Inst, Dept Biomed Sci, DK-220 Copenhagen, Denmark
[2] Univ Copenhagen, Panum Inst, NNF Ctr Basic Metab Res, DK-220 Copenhagen, Denmark
关键词
BETA-CELL FUNCTION; GLP-1; RECEPTOR; CARDIOVASCULAR OUTCOMES; HEART-FAILURE; DOUBLE-BLIND; FOOD-INTAKE; TYPE-2; LIRAGLUTIDE; GLUCOSE; SEMAGLUTIDE;
D O I
10.21037/atm.2019.01.09
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页数:6
相关论文
共 31 条
[1]   GLP-1 Receptor Expression Within the Human Heart [J].
Baggio, Laurie L. ;
Yusta, Bernardo ;
Mulvihill, Erin E. ;
Cao, Xiemin ;
Streutker, Catherine J. ;
Butany, Jagdish ;
Cappola, Thomas P. ;
Margulies, Kenneth B. ;
Drucker, Daniel J. .
ENDOCRINOLOGY, 2018, 159 (04) :1570-1584
[2]   Effects of Exenatide on Measures of β-Cell Function After 3 Years in Metformin-Treated Patients With Type 2 Diabetes [J].
Bunck, Mathijs C. ;
Corner, Anja ;
Ellasson, Bjorn ;
Heine, Robert J. ;
Shaginian, Rimma M. ;
Taskinen, Marja-Riitta ;
Smith, Ulf ;
Yki-Jarvinen, Hannele ;
Diamant, Michaela .
DIABETES CARE, 2011, 34 (09) :2041-2047
[3]  
Davies MJ, 2018, DIABETES CARE, V41, P2669, DOI [10.2337/dci18-0033, 10.1007/s00125-018-4729-5]
[4]   Discovery, characterization, and clinical development of the glucagon-like peptides [J].
Drucker, Daniel J. ;
Habener, Joel F. ;
Holst, Jens Juul .
JOURNAL OF CLINICAL INVESTIGATION, 2017, 127 (12) :4217-4227
[5]   The Cardiovascular Biology of Glucagon-like Peptide-1 [J].
Drucker, Daniel J. .
CELL METABOLISM, 2016, 24 (01) :15-30
[6]   The Glucagonostatic and Insulinotropic Effects of Glucagon-Like Peptide 1 Contribute Equally to Its Glucose-Lowering Action [J].
Hare, Kristine J. ;
Vilsboll, Tina ;
Asmar, Meena ;
Deacon, Carolyn F. ;
Knop, Filip K. ;
Holst, Jens J. .
DIABETES, 2010, 59 (07) :1765-1770
[7]   Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial [J].
Hernandez, Adrian F. ;
Green, Jennifer B. ;
Janmohamed, Salim ;
D'Agostino, Ralph B., Sr. ;
Granger, Christopher B. ;
Jones, Nigel P. ;
Leiter, Lawrence A. ;
Rosenberg, Anne E. ;
Sigmon, Kristina N. ;
Somerville, Matthew C. ;
Thorpe, Karl M. ;
McMurray, John J. V. ;
Del Prato, Stefano .
LANCET, 2018, 392 (10157) :1519-1529
[8]   Semaglutide improves postprandial glucose and lipid metabolism, and delays first-hour gastric emptying in subjects with obesity [J].
Hjerpsted, Julie B. ;
Flint, Anne ;
Brooks, Ashley ;
Axelsen, Mads B. ;
Kvist, Trine ;
Blundell, John .
DIABETES OBESITY & METABOLISM, 2018, 20 (03) :610-619
[9]   Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes [J].
Holman, Rury R. ;
Bethel, M. Angelyn ;
Mentz, Robert J. ;
Thompson, Vivian P. ;
Lokhnygina, Yuliya ;
Buse, John B. ;
Chan, Juliana C. ;
Choi, Jasmine ;
Gustavson, Stephanie M. ;
Iqbal, Nayyar ;
Maggioni, Aldo P. ;
Marso, Steven P. ;
Ohman, Peter ;
Pagidipati, Neha J. ;
Poulter, Neil ;
Ramachandran, Ambady ;
Zinman, Bernard ;
Hernandez, Adrian F. .
NEW ENGLAND JOURNAL OF MEDICINE, 2017, 377 (13) :1228-1239
[10]   The physiology of glucagon-like peptide 1 [J].
Holst, Jens Juul .
PHYSIOLOGICAL REVIEWS, 2007, 87 (04) :1409-1439