Opportunities and challenges in targeting genes for therapy

被引：22
|
作者：
Gruenert, DC [1 ]
机构：
[1] Univ Calif San Francisco, Gene Therapy Core Ctr, Cardiovasc Res Inst, Dept Lab Med, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Gene Therapy Core Ctr, Cardiovasc Res Inst, Dept Stomatol, San Francisco, CA 94143 USA
来源：
GENE THERAPY | 1999年 / 6卷 / 08期
关键词：
D O I：
10.1038/sj.gt.3301011
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：1347 / 1348
页数：2
相关论文
共 50 条
  • [1] Opportunities and challenges in targeting genes for therapy
    D C Gruenert
    Gene Therapy, 1999, 6 : 1347 - 1348
  • [2] Targeting pan-essential genes in cancer: Challenges and opportunities
    Chang, Liang
    Ruiz, Paloma
    Ito, Takahiro
    Sellers, William R.
    CANCER CELL, 2021, 39 (04) : 466 - 479
  • [3] Lung Cancer Therapy Targeting Histone Methylation: Opportunities and Challenges
    Chen, Yuchen
    Liu, Xinran
    Li, Yangkai
    Quan, Chuntao
    Zheng, Ling
    Huang, Kun
    COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2018, 16 : 211 - 223
  • [4] Targeting CDK2 in cancer: challenges and opportunities for therapy
    Tadesse, Solomon
    Anshabo, Abel T.
    Portman, Neil
    Lim, Elgene
    Tilley, Wayne
    Caldon, C. Elizabeth
    Wang, Shudong
    DRUG DISCOVERY TODAY, 2020, 25 (02) : 406 - 413
  • [5] Targeting nanoparticles for diagnosis and therapy of bone tumors: Opportunities and challenges
    Gao, Xin
    Li, Lin
    Cai, Xiaopan
    Huang, Quan
    Xiao, Jianru
    Cheng, Yiyun
    BIOMATERIALS, 2021, 265
  • [6] Targeting hypercholesterolaemia: challenges and opportunities
    Crea, Filippo
    EUROPEAN HEART JOURNAL, 2023, 44 (25) : 2263 - 2266
  • [7] Challenges and opportunities in targeting metabolism
    Birsoy, Kivanc
    Chandel, Navdeep S.
    Fendt, Sarah-Maria
    Green, Douglas R.
    Li, Xiaoling
    Muoio, Deborah M.
    CELL CHEMICAL BIOLOGY, 2023, 30 (09) : 999 - 1001
  • [8] Targeting undruggable protein KRAS for cancer therapy: novel opportunities and challenges
    Yang, Xin
    Li, Xiang
    Zhang, Yue-Lin
    Zhang, Sheng-Nan
    Zhang, Miao
    Sun, Chong
    Yang, Li
    Liu, Hong-Min
    Yuan, Shuo
    FUTURE MEDICINAL CHEMISTRY, 2025, 17 (02) : 143 - 147
  • [9] Opportunities and Challenges in Targeting Ubiquitin Modification and Degradation for Prostate Cancer Therapy
    Peng, Yun-Hua
    Liu, Sha
    Cui, Li
    Liu, Jian-Kang
    Long, Jian-Gang
    PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2023, 50 (04) : 782 - 794
  • [10] Targeting Host Cell Surface Nucleolin for RSV Therapy: Challenges and Opportunities
    Mastrangelo, Peter
    Norris, Michael J.
    Duan, Wenming
    Barrett, Edward G.
    Moraes, Theo J.
    Hegele, Richard G.
    VACCINES, 2017, 5 (03):
12345