pH-Responsive Size-Tunable Self-Assembled DNA Dendrimers

被引：78

作者：

Zhou, Tao ^{[1
]}

Chen, Ping ^{[3
]}

Niu, Lin ^{[4
,5
]}

Jin, Juan ^{[1
,2
]}

Liang, Dehai ^{[4
,5
]}

Li, Zhibo ^{[3
]}

Yang, Zhongqiang ^{[1
]}

Liu, Dongsheng ^{[1
]}

机构：

[1] Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Organ Optoelect & Mol Engn, Beijing 100084, Peoples R China

[2] Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China

[3] Chinese Acad Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China

[4] Peking Univ, Coll Chem & Mol Engn, Dept Polymer Sci & Engn, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China

[5] Peking Univ, Minist Educ, Coll Chem & Mol Engn, Key Lab Polymer Chem & Phys, Beijing 100871, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 45期

基金：

中国国家自然科学基金;

关键词：

dendrimers; DNA; pH responsiveness; self-assembly; size tunable;

D O I：

10.1002/anie.201205862

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Putting the DNA in dendrimers: A strategy to swiftly prepare DNA dendrimers based solely on DNA self-assembly is presented. This technique produces highly pure DNA dendrimers with an excellent yield of high generation dendrimers. The incorporation of molecular motors (i-motifs) into the DNA dendrimers allows for a change in size (up to 30%) in response to changing pH values (see scheme). Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：11271 / 11274

页数：4

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