Laparoscopic vs. Open Cholecystectomy for Cirrhotic Patients: A Systematic Review and Meta-Analysis

被引:20
作者
Cheng, Yao [1 ]
Xiong, Xian-Ze [1 ]
Wu, Si-Jia [1 ]
Lin, Yi-Xin [1 ]
Cheng, Nan-Sheng [1 ]
机构
[1] Sichuan Univ, W China Hosp, Dept Bile Duct Surg, Chengdu 610041, Sichuan Provinc, Peoples R China
基金
中国国家自然科学基金;
关键词
Liver cirrhosis; Gallstones; Laparoscopic cholecystectomy; Open cholecystectomy; Systematic review; Meta-analysis; LIVER-CIRRHOSIS; GALLSTONES; PREVALENCE; SURGERY; CONTRAINDICATION; DISEASE;
D O I
10.5754/hge11688
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background/Aims: To compare the safety and effectiveness of laparoscopic cholecystectomy (LC) versus open cholecystectomy (OC) for cirrhotic patients. Methodology: The Cochrane Library, MEDLINE, Science Citation Index Expanded, EM BASE and CBM (Chinese Biomedical Database) were searched until August 2011 to indentify relevant and eligible studies. Results: Twenty four articles with 1366 cirrhotic patients were included. All patients were allocated to the LC group (n=720) or the OC group (n=646). They were primarily in Child-Pugh class A (n=996, 72.9%) and class B (n=354, 25.9%). Meta-analysis of 5 randomized controlled trials (n=284) indicated LC group was associated with the following advantages: significant lower surgery-related morbidity, less postoperative complications (e.g. incision hernia, wound infection), shorter hospital stay and less loss of blood. There were no significant differences in the intra-hospital mortality and total operative time between the two groups. Meta-analysis of 19 non-randomized studies (n=1082) showed similar results in favour of LC group. In addition, it showed significant lower intra-hospital mortality and less total operative time in the LC group than the OC group. Conclusions: LC is safe and offers various significant benefits over OC. Thus, it should be recommended for compensated cirrhotic patients.
引用
收藏
页码:1727 / 1734
页数:8
相关论文
共 49 条
[41]   Epidemiology of Gallstones [J].
Stinton, Laura M. ;
Myers, Robert P. ;
Shaffer, Eldon A. .
GASTROENTEROLOGY CLINICS OF NORTH AMERICA, 2010, 39 (02) :157-+
[42]  
Wang RT, 2011, CHINA MOD DOCTOR, V49, P132
[43]  
[辛建 Xin Jian], 2010, [华中科技大学学报. 医学版, Acta Medicinae Universitatis Scientiae et Technologiae Huazhong], V39, P532
[44]  
Yang ZH, 2003, FUJIAN MED J, V25, P93
[45]  
YERDEL MA, 1993, SURG LAPAROSC ENDOSC, V3, P180
[46]   Laparoscopic versus open cholecystectomy in cirrhotic patients - A prospective study [J].
Yerdel, MA ;
Koksoy, C ;
Aras, N ;
Orita, K .
SURGICAL LAPAROSCOPY & ENDOSCOPY, 1997, 7 (06) :483-486
[47]  
Yuan JT, 2009, W CHINA MED J, V24, P1649
[48]  
Zhen JH, 2006, GUANGDONG MED J, V29, P1056
[49]  
[朱玉华 Zhu Yuhua], 2004, [上海第二医科大学学报, Acta Universitatis Medicinalis Secondae Shanghai], V24, P463