Prenatal determinants of childhood obesity: a review of risk factors

被引：27

作者：

Liao, Xiang-Peng ^{[1
,2
,3
]}

Yu, Yamei ^{[4
]}

Marc, Isabelle ^{[5
,6
]}

Dubois, Lise ^{[4
]}

Abdelouahab, Nadia ^{[2
,3
]}

Bouchard, Luigi ^{[7
]}

Wu, Yan-Ting ^{[8
,9
]}

Ouyang, Fengxiu ^{[10
,11
]}

Huang, Heng-Feng ^{[8
,9
]}

Fraser, William D. ^{[2
,3
]}

机构：

[1] Second Mil Med Univ, Shanghai Gongli Hosp, Dept Pediat, Shanghai, Peoples R China

[2] Univ Sherbrooke, CRCHUS, Quebec City, PQ J1H 5N4, Canada

[3] Univ Sherbrooke, Dept Obstet & Gynecol, Quebec City, PQ J1H 5N4, Canada

[4] Univ Ottawa, Fac Med, Sch Epidemiol & Publ Hlth, Ottawa, ON K1G 5Z3, Canada

[5] Univ Laval, Fac Med, Ctr Hosp Univ Quebec, Res Ctr, Quebec City, PQ G1V 4G2, Canada

[6] Univ Laval, Fac Med, Dept Pediat, Quebec City, PQ G1V 4G2, Canada

[7] Univ Sherbrooke, CIUSSS SLSJ, Dept Med Biol, Saguenay, PQ G7H 7K9, Canada

[8] Shanghai Jiao Tong Univ, Sch Med, Int Peace Matern & Child Hlth Hosp, Shanghai, Peoples R China

[9] Shanghai Jiao Tong Univ, Sch Med, Inst Embryofetal Original Adult Dis, Shanghai, Peoples R China

[10] Xinhua Hosp, Minist Educ, Shanghai Key Lab Childrens Environm Hlth, Shanghai, Peoples R China

[11] Shanghai Jiao Tong Univ, Sch Med, Shanghai, Peoples R China

来源：

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY | 2019年 / 97卷 / 03期

基金：

加拿大健康研究院; 中国国家自然科学基金;

关键词：

risk factors; obesity; pregnancy; body mass index; childhood; BODY-MASS INDEX; PERSISTENT ORGANIC POLLUTANTS; RAPID WEIGHT-GAIN; PREGNANCY AND/OR LACTATION; GENOME-WIDE ASSOCIATION; MATERNAL SMOKING; GUT MICROBIOTA; BIRTH-WEIGHT; EARLY-LIFE; PERFLUOROALKYL SUBSTANCES;

D O I：

10.1139/cjpp-2018-0403

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Childhood obesity is a predictor of adult obesity and has its roots in the pre-pregnancy or pregnancy period. This review presents an overview of the prenatal risk factors for childhood obesity, which were categorized into 2 groups: biological risk factors (maternal pre-pregnancy body mass index, gestational weight gain, diabetes in pregnancy, and caesarean section), and environmental and behavioural risk factors (maternal smoking and exposure to obesogens, maternal dietary patterns, maternal intestinal microbiome and antibiotics exposure, and maternal psychosocial stress). Identifying modifiable predisposing prenatal factors for obesity will inform further development of inventions to prevent obesity over the life course, and future directions for research and intervention are discussed.

引用

页码：147 / 154

页数：8

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