Therapeutic potentials of herbal drugs for Alzheimer's disease-An overview

被引：0
作者：
Kumar, Anil [1 ]
Singh, Arti [1 ]
Aggarwal, Archi [1 ]
机构：
[1] Panjab Univ, Div Pharmacol, Univ Inst Pharmaceut Sci, UGC Ctr Adv Study, Chandigarh 160014, India
来源：
INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY | 2017年 / 55卷 / 02期
关键词：
Acetylcholinesterase inhibitors; N-methyl D-aspartate receptor antagonist; amyloid beta; neurofibrillary tangles; INDUCED COGNITIVE IMPAIRMENT; INHIBITORY-ACTIVITY; GINKGO-BILOBA; OXIDATIVE STRESS; DOUBLE-BLIND; IN-VITRO; NEUROPROTECTIVE ROLE; NATURAL-PRODUCTS; BACOPA-MONNIERA; MEDICINAL HERB;
D O I：
暂无
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Alzheimer's disease (AD) is a well known progressive neurodegenerative disorder having complex pathophysiology. Currently, drugs that are used symptomatically in the treatment of AD include acetylcholinesterase inhibitors (AChEIs) (rivastigmine, galantamine, donepezil) and N-methyl D-aspartate (NMDA) receptor antagonist (memantine). Limited bioavailability of these drugs stresses continuity of search for novel therapeutics for this slow growing but complex disease. Herbal drugs are being used to treat memory related problems, including Alzheimer's from time immemorial. Both preclinical and clinical studies demonstrated the therapeutic potential of herbal drugs for the prevention of AD. Herbal drugs have been shown to be effective against Alzheimer's possibly due to their pleiotropic and multifaceted action that includes antioxidants, anti-inflammatory and neuroprotective action. This review highlights the therapeutic potential of herbal drugs for the treatment of AD.
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页码：63 / 73
页数：11
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