Mathematical modeling of fetal organ growth using the Rossavik growth model .5. Cerebellum

Growth of the fetal cerebellum was monitored by transverse cerebellar diameter (CD) from 14 to 39 weeks menstrual age in 125 normal Japanese fetuses. The growth curve for this parameter was determined using a Rossavik growth model [p = c(t)(k+s(t))]. An R(2) value of 95.5% was obtained for CD. Variability analysis indicated a progressive increase in variability with fetal age for this parameter. Variability data were used with the growth curve model to determine a standard curve for this parameter. This standard curve provides a superior means to evaluate normal fetal cerebellar growth in the fetus and to identify cerebellar abnormalities in utero.