High frequency of mutator strains among human uropathogenic Escherichia coli isolates

被引：142

作者：

Denamur, E ^{[1
]}

Bonacorsi, S ^{[1
]}

Giraud, A ^{[1
]}

Duriez, P ^{[1
]}

Hilali, F ^{[1
]}

Amorin, C ^{[1
]}

Bingen, E ^{[1
]}

Andremont, A ^{[1
]}

Picard, B ^{[1
]}

Taddei, F ^{[1
]}

Matic, I ^{[1
]}

机构：

[1] Univ Paris 05, Fac Med Nucl, INSERM, EPI 9916, F-75730 Paris 15, France

来源：

JOURNAL OF BACTERIOLOGY | 2002年 / 184卷 / 02期

关键词：

D O I：

10.1128/JB.184.2.605-609.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

By using a panel of 603 commensal and pathogenic Escherichia coli and Shigella isolates, we showed that mutation rates of strains vary considerably among different ecotypes. Uropathogenic strains had the highest frequency of mutators, while strains from patients with bacteremia had the lowest mutation rates. No correlation between the mutation rates and antibiotic resistance was observed among the studied strains.

引用

页码：605 / 609

页数：5

共 25 条

[1] Phylogenetic analysis of Escherichia coli strains causing neonatal meningitis suggests horizontal gene transfer from a predominant pool of highly virulent B2 group strains [J].

Bingen, E ;

Picard, B ;

Brahimi, N ;

Mathy, S ;

Desjardins, P ;

Elion, J ;

Denamur, E .

JOURNAL OF INFECTIOUS DISEASES, 1998, 177 (03) :642-650

[2] Effects of environment on compensatory mutations to ameliorate costs of antibiotic resistance [J].

Björkman, J ;

Nagaev, I ;

Berg, OG ;

Hughes, D ;

Andersson, DI .

SCIENCE, 2000, 287 (5457) :1479-1482

[3] Evolutionary implications of the frequent horizontal transfer of mismatch repair genes [J].

Denamur, E ;

Lecointre, G ;

Darlu, P ;

Tenaillon, O ;

Acquaviva, C ;

Sayada, C ;

Sunjevaric, I ;

Rothstein, R ;

Elion, J ;

Taddei, F ;

Radman, M ;

Matic, I .

CELL, 2000, 103 (05) :711-721

[4] Commensal Escherichia coli isolates are phylogenetically distributed among geographically distinct human populations [J].

Duriez, P ;

Clermont, O ;

Bonacorsi, S ;

Bingen, E ;

Chaventre, A ;

Elion, J ;

Picard, B ;

Denamur, E .

MICROBIOLOGY-SGM, 2001, 147 :1671-1676

[5]

Funchain P, 2000, GENETICS, V154, P959

[6] Costs and benefits of high mutation rates: Adaptive evolution of bacteria in the mouse gut [J].

Giraud, A ;

Matic, I ;

Tenaillon, O ;

Clara, A ;

Radman, M ;

Fons, M ;

Taddei, F .

SCIENCE, 2001, 291 (5513) :2606-2608

[7] Prevalence of virulence genes and clonality in Escherichia coli strains that cause bacteremia in cancer patients [J].

Hilali, F ;

Ruimy, R ;

Saulnier, P ;

Barnabé, C ;

Lebouguénec, C ;

Tibayrenc, M ;

Andremont, A .

INFECTION AND IMMUNITY, 2000, 68 (07) :3983-3989

[8] High mutation frequencies among Escherichia coli and Salmonella pathogens [J].

LeClerc, JE ;

Li, BG ;

Payne, WL ;

Cebula, TA .

SCIENCE, 1996, 274 (5290) :1208-1211

[9] Proliferation of mutators in a cell population [J].

Mao, EF ;

Lane, L ;

Lee, J ;

Miller, JH .

JOURNAL OF BACTERIOLOGY, 1997, 179 (02) :417-422

[10] Highly variable mutation rates in commensal and pathogenic Escherichia coli [J].

Matic, I ;

Radman, M ;

Taddei, F ;

Picard, B ;

Doit, C ;

Bingen, E ;

Denamur, E ;

Elion, J .

SCIENCE, 1997, 277 (5333) :1833-1834

← 1 2 3 →