Investigating the effect of a magnetic field on dose distributions at phantom-air interfaces using PRESAGE® 3D dosimeter and Monte Carlo simulations

被引:24
作者
Costa, Filipa [1 ,2 ]
Doran, Simon J. [3 ]
Hanson, Ian M. [1 ,2 ]
Nill, Simeon [1 ,2 ]
Billas, Ilias [4 ]
Shipley, David [4 ]
Duane, Simon [4 ]
Adamovics, John [5 ]
Oelfke, Uwe [1 ,2 ]
机构
[1] Inst Canc Res, Joint Dept Phys, Sutton SM2 5NG, Surrey, England
[2] Royal Marsden NHS Fdn Trust, Sutton SM2 5NG, Surrey, England
[3] Inst Canc Res, CRUK Canc Imaging Ctr, London SM2 5NG, England
[4] Natl Phys Lab, Metrol Med Phys, Hampton Rd, Teddington TW11 0LW, Middx, England
[5] Rider Univ, Dept Biol & Chem, Lawrenceville, NJ 08648 USA
基金
英国工程与自然科学研究理事会;
关键词
3D dosimetry; Monte Carlo; optical-CT; PRESAGE; MR-linac; quality assurance; MV RADIOTHERAPY ACCELERATOR; OPTICAL CT; MRI SCANNER; IMRT; RESONANCE; LINAC; FEASIBILITY; IRRADIATION; IMPACT; QA;
D O I
10.1088/1361-6560/aaaca2
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Dosimetric quality assurance (QA) of the new Elekta Unity (MR-linac) will differ from the QA performed of a conventional linac due to the constant magnetic field, which creates an electron return effect (ERE). In this work we aim to validate PRESAGE (R) dosimetry in a transverse magnetic field, and assess its use to validate the research version of the Monaco TPS of the MR-linac. Cylindrical samples of PRESAGE (R) 3D dosimeter separated by an air gap were irradiated with a cobalt-60 unit, while placed between the poles of an electromagnet at 0.5 T and 1.5 T. This set-up was simulated in EGSnrc/Cavity Monte Carlo (MC) code and relative dose distributions were compared with measurements using 1D and 2D gamma criteria of 3% and 1.5 mm. The irradiation conditions were adapted for the MR-linac and compared with Monaco TPS simulations. Measured and EGSnrc/Cavity simulated profiles showed good agreement with a gamma passing rate of 99.9% for 0.5 T and 99.8% for 1.5 T. Measurements on the MR-linac also compared well with Monaco TPS simulations, with a gamma passing rate of 98.4% at 1.5 T. Results demonstrated that PRESAGE (R) can accurately measure dose and detect the ERE, encouraging its use as a QA tool to validate the Monaco TPS of the MR-linac for clinically relevant dose distributions at tissue-air boundaries.
引用
收藏
页数:10
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