Phomoxins B and C:: Polyketides from an endophytic fungus of the genus Eupenicillium

被引：29

作者：

Davis, RA ^{[1
]}

Andjic, V

Kotiw, M

Shivas, RG

机构：

[1] Griffith Univ, Chem Biol Program, Eskitis Inst, Brisbane, Qld 4111, Australia

[2] Univ So Queensland, Dept Biol & Phys Sci, Toowoomba, Qld 4351, Australia

[3] Dept Primary Ind & Fisheries, Indooroopilly, Qld 4068, Australia

来源：

PHYTOCHEMISTRY | 2005年 / 66卷 / 23期

关键词：

endophytic fungus; Eupenicillium sp; Glochidion ferdinandi; natural products; polyketides; phomoxin B; phomoxin C; eupenoxide; cyclic carbonate;

D O I：

10.1016/j.phytochem.2005.09.004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chemical investigations of the culture broth from in endophytic fungus Eupenicillilim sp. have afforded two natural products phomoxins B (1) and C (2) as well as the previously reported fungal metabolite eupenoxide (3). Compounds 1 and 2 both contain a cyclic carbonate moiety that is rare among natural products. This paper reports the full spectroscopic characterisation of phomoxins B (1) and C (2) by NMR, UV, IR and MS data. All compounds were inactive against a panel of nosocomial microbes. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：2771 / 2775

页数：5

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