Rhodium-catalyzed intramolecular [4+2] cycloadditions of alkynyl halides

被引：43

作者：

Yoo, WJ ^{[1
]}

Allen, A ^{[1
]}

Villeneuve, K ^{[1
]}

Tam, W ^{[1
]}

机构：

[1] Univ Guelph, Guelph Waterloo Ctr Grad Work Chem & Biochem, Dept Chem, Guelph, ON N1G 2W1, Canada

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 26期

关键词：

D O I：

10.1021/ol052412o

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Cationic rhodium(l)-catalyzed intramolecular [4 + 2] cycloadditions of diene-tethered alkynyl halides were found to occur in good yields (70-87%). The halide moiety is compatible with the cycloaddition reactions, and no oxidative insertion to the alkynyl halide was observed. The halogen-containing cycloadducts could be transformed into a variety of products that are difficult or impossible to obtain via direct cycloaddition.

引用

页码：5853 / 5856

页数：4

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