Physicochemical Properties and Biocompatibility of White Dextrin Modified Injectable Calcium-Magnesium Phosphate Cement

被引：4

作者：

Chen, Fangping ^{[1
,2
]}

Liu, Changsheng ^{[1
,2
]}

Wei, Jie ^{[2
,3
]}

Chen, Xiaolong ^{[3
]}

机构：

[1] E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

[2] E China Univ Sci & Technol, Sch Mat Sci & Engn, Minist Educ, Key Lab Ultrafine Mat, Shanghai 200237, Peoples R China

[3] E China Univ Sci & Technol, Engn Res Ctr Biomed Mat, Minist Educ, Shanghai 200237, Peoples R China

来源：

INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY | 2012年 / 9卷 / 05期

基金：

上海市自然科学基金; 美国国家科学基金会;

关键词：

BONE REGENERATION; IN-VITRO; RHEOLOGICAL PROPERTIES; SURFACE; DIFFERENTIATION; PROLIFERATION; BIOACTIVITY; ICODEXTRIN; AGENTS;

D O I：

10.1111/j.1744-7402.2011.02705.x

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

The objective of this study was to develop anti-washout and fast-setting calciummagnesium phosphate cement (as-CMP) by introducing white dextrin (WD) and magnesium phosphate cement (MPC) to CPC. The results showed that WD imparted anti-washout to the as-CMP paste, whereas MPC simultaneously improved the paste anti-washout and fast-setting. The synergistic effect of MPC and WD obviously shortened the setting time of as-CMP. The WD did not affect the phase evolution and microstructure of the paste. Furthermore, all samples were biocompatible and as-CMP exhibited the best cell metabolic activity, cell attachment, and proliferation, which would provide basic data for the clinical application.

引用

页码：979 / 990

页数：12

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