Concurrent group treatment for hepatitis C: Implementation and outcomes in a methadone maintenance treatment program

被引:51
作者
Stein, Melissa R. [1 ,2 ]
Soloway, Irene J. [2 ]
Jefferson, Karen S. [2 ]
Roose, Robert J. [2 ,3 ]
Arnsten, Julia H. [1 ,2 ,4 ]
Litwin, Alain H. [1 ,2 ]
机构
[1] Montefiore Med Ctr, Albert Einstein Coll Med, Dept Med, Div Gen Internal Med, Bronx, NY 10467 USA
[2] Montefiore Med Ctr, Albert Einstein Coll Med, Dept Psychiat & Behav Sci, Div Subst Abuse, Bronx, NY 10467 USA
[3] Montefiore Med Ctr, Albert Einstein Coll Med, Dept Family & Social Med, Bronx, NY 10467 USA
[4] Montefiore Med Ctr, Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY 10467 USA
关键词
HCV; Chronic hepatitis C; IDU; Methadone maintenance; Group treatment; INJECTION-DRUG USERS; VIRUS-INFECTION; GLOBAL EPIDEMIOLOGY; ANTIVIRAL TREATMENT; HIV; SERVICES; CARE; MODEL; MANAGEMENT; MORTALITY;
D O I
10.1016/j.jsat.2012.08.007
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Chronic hepatitis C virus (HCV) infection is highly prevalent among current and former drug users. However, the minority of patients enrolled in drug treatment programs have initiated HCV treatment. New models are needed to overcome barriers to care. In this retrospective study, we describe the implementation and outcomes of 42 patients treated in a concurrent group treatment (CGT) program. Patients participated in weekly provider-led group treatment sessions which included review of side effects; discussion of adherence and side effect management; administration of interferon injections; brief physical examination; and ended with brief meditation. Of the first 27 patients who initiated CGT, 42% achieved a sustained viral response. In addition, 87% (13/15) of genotype-1 infected patients treated with direct acting antiviral agent achieved an undetectable viral load at 24 weeks. The CGT model may be effective in overcoming barriers to treatment and improving adherence and outcomes among patients enrolled in drug treatment programs. (C) 2012 Elsevier Inc. All rights reserved.
引用
收藏
页码:424 / 432
页数:9
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