PHLPP1 Deactivates Akt and has a Tumour Suppressive Role in Human Melanoma

被引：0
|
作者：
Jin, L. [1 ]
Li, D. [1 ]
Wang, C. Y. [2 ]
Tseng, H. -Y [1 ]
Wilmott, J. S. [3 ]
Yosufi, B. [3 ]
Yan, X. G. [1 ]
Scolyer, R. A. [3 ]
Guo, S. T. [2 ]
Zhang, X. D. [1 ]
机构：
[1] Univ Newcastle, Callaghan, NSW 2308, Australia
[2] Shanxi Canc Hosp & Inst, Taiyuan, Peoples R China
[3] Univ Sydney, Sydney, NSW 2006, Australia
来源：
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT | 2013年 / 11卷
关键词：
D O I：
暂无
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
引用
收藏
页码：18 / 18
页数：1
相关论文
共 50 条
  • [1] Oncogenic suppression of PHLPP1 in human melanoma
    Dong, L.
    Jin, L.
    Tseng, H-Y
    Wang, C. Y.
    Wilmott, J. S.
    Yosufi, B.
    Yan, X. G.
    Jiang, C. C.
    Scolyer, R. A.
    Zhang, X. D.
    Guo, S. T.
    ONCOGENE, 2014, 33 (39) : 4756 - 4766
  • [2] Oncogenic suppression of PHLPP1 in human melanoma
    L Dong
    L Jin
    H-Y Tseng
    C Y Wang
    J S Wilmott
    B Yosufi
    X G Yan
    C C Jiang
    R A Scolyer
    X D Zhang
    S T Guo
    Oncogene, 2014, 33 : 4756 - 4766
  • [3] PHLPP1 is a metastasis suppressor in melanoma
    Dai, Meng
    Yu, Yanlin
    AGING-US, 2018, 10 (09): : 2214 - 2215
  • [4] Akt activity regulates the stability of the PHLPP1 phosphatase
    Warfel, Noel
    Newton, Alexandra
    CANCER RESEARCH, 2009, 69
  • [5] PHLPP1 mediates melanoma metastasis suppression through repressing AKT2 activation
    Yu, Yanlin
    Dai, Meng
    Lu, Andrew
    Yu, Ellen
    Merlino, Glenn
    ONCOGENE, 2018, 37 (17) : 2225 - 2236
  • [6] PHLPP1 mediates melanoma metastasis suppression through repressing AKT2 activation
    Yanlin Yu
    Meng Dai
    Andrew Lu
    Ellen Yu
    Glenn Merlino
    Oncogene, 2018, 37 : 2225 - 2236
  • [7] Identification of PHLPP1 as a novel metastasis suppressor in melanoma
    Yu, Yanlin
    Lu, Andrew
    Dai, Meng
    Merlino, Glenn
    CANCER RESEARCH, 2013, 73 (08)
  • [8] Vitamin E Facilitates the Inactivation of the Kinase Akt by the Phosphatase PHLPP1
    Huang, Po-Hsien
    Chuang, Hsiao-Ching
    Chou, Chih-Chien
    Wang, Huiling
    Lee, Su-Lin
    Yang, Hsiao-Ching
    Chiu, Hao-Chieh
    Kapuriya, Naval
    Wang, Dasheng
    Kulp, Samuel K.
    Chen, Ching-Shih
    SCIENCE SIGNALING, 2013, 6 (267)
  • [9] Detection of PHLPP1α/β in Human and Mouse Brain by Different Anti-PHLPP1 Antibodies
    Jackson, Travis C.
    Bayir, Huelya
    Ikonomovic, Milos D.
    Janesko-Feldman, Keri
    Mi, Zaichuan
    Gao, Tianyan
    Jackson, Edwin K.
    Kochanek, Patrick M.
    SCIENTIFIC REPORTS, 2015, 5
  • [10] Exploitation of the Ability of γ-Tocopherol to Facilitate Membrane Co-localization of Akt and PHLPP1 to Develop PHLPP1-Targeted Akt Inhibitors
    Yan, Ribai
    Chuang, Hsiao-Ching
    Kapuriya, Naval
    Chou, Chih-Chien
    Lai, Po-Ting
    Chang, Hsin-Wen
    Yang, Chia-Ning
    Kulp, Samuel K.
    Chen, Ching-Shih
    JOURNAL OF MEDICINAL CHEMISTRY, 2015, 58 (05) : 2290 - 2298
12345