Venereal transmission of canine visceral leishmaniasis

被引：95

作者：

Silva, Fabiana L. ^{[1
]}

Oliveira, Raquel G. ^{[1
]}

Silva, Teane M. A. ^{[1
]}

Xavier, Mariana N. ^{[1
]}

Nascimento, Ernane F. ^{[1
]}

Santos, Renato L. ^{[1
]}

机构：

[1] Univ Fed Minas Gerais, Escola Vet, Dept Clin & Cirurg Vet, BR-31270901 Belo Horizonte, MG, Brazil

来源：

VETERINARY PARASITOLOGY | 2009年 / 160卷 / 1-2期

关键词：

Leishmania chagasi; Visceral leishmaniasis; Dog; Venereal transmission; PHLEBOTOMINE SAND FLIES; GENITAL LESIONS; AMASTIGOTES; DIAGNOSIS; BLOOD;

D O I：

10.1016/j.vetpar.2008.10.079

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Leishmania chagasi, the agent of visceral leishmaniasis in dogs in the Americas has a tropism to the male genital system, particularly the epididymis, prepuce, and glans penis, resulting in shedding of Leishmania in the semen. The goal of this study was to verify the possibility of venereal transmission of L chagasi. Twelve Leishmania-free bitches, housed in the absence of the insect vector, copulated with multiple naturally infected dogs that were shedding Leishmania in the semen. PCR analysis of serially collected ejaculates indicated that shedding of Leishmania in the semen is intermittent. Three bitches seroconverted, and six were PCR positive by the end of the experimental period (165 days after the last copulation). These data support the notion that L. chagasi may be sexually transmitted from naturally infected dogs to susceptible bitches in the absence of the biological insect vector. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：55 / 59

页数：5

共 28 条

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