Discrepancies in insulin-like growth factor signaling? No, not really

被引:14
作者
Conover, Cheryl A. [1 ]
机构
[1] Mayo Clin, Endocrine Res Uni4, 200 First St SW, Rochester, MN 55905 USA
关键词
IGF; IGF-I receptor; IGFBP; PLASMA PROTEIN-A; FACTOR-I; IGF-I; STEM-CELLS; MICE; BINDING; NEURODEGENERATION; ATHEROSCLEROSIS; RESISTANCE; INSIGHTS;
D O I
10.1016/j.ghir.2016.10.005
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Why do studies on insulin-like growth factors (IGFs) and IGF signaling seem so contradictory? The answer is "It depends". This mini-review will explore a few of the factors that are likely to contribute to a seemingly confusing message. Most of the evidence comes from experimental animal models. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码:42 / 44
页数:3
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