A novel procedure for the mechanical characterization of the uterine cervix during pregnancy

被引：35

作者：

Badir, Sabrina ^{[1
]}

Bajka, Michael ^{[3
]}

Mazza, Edoardo ^{[1
,2
]}

机构：

[1] Swiss Fed Inst Technol Zurich, Dept Mech & Proc Engn, CH-8092 Zurich, Switzerland

[2] EMPA, Swiss Fed Labs Mat Testing & Res, CH-8600 Dubendorf, Switzerland

[3] Univ Zurich Hosp, Dept Obstet & Gynecol, CH-8091 Zurich, Switzerland

来源：

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS | 2013年 / 27卷

关键词：

Uterine cervix; Aspiration experiment; In-vivo measurements; Inverse analysis; HUMAN LIVER; AGE;

D O I：

10.1016/j.jmbbm.2012.11.020

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

An in-vivo measurement procedure is presented to characterize the mechanical behavior of human uterine cervix during pregnancy. Based on the aspiration method, a new instrument was developed to provide an inherently safe and easy-to-use mechanical testing technique. Initial measurements were performed on non-pregnant women to develop an appropriate measurement protocol. An inverse analysis was carried out to determine representative model equations for cervical tissue. This model was used in a FE based parametric study focusing on the uncertainties related to the experiment. On this basis, a novel procedure was established which enabled for the first time to conduct mechanical measurements on 50 pregnant women in over 600 applications during gestation. An inverse analysis of the average tissue response at each trimester was performed to determine representative model equations for the cervix in the course of pregnancy. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：143 / 153

页数：11

共 26 条

[1]

Akins M., 2010, J BIOMEDICAL OPTICS, V15

[2]

[Anonymous], THESIS MIT

[3] The pipette aspiration applied to the local stiffness measurement of soft tissues [J].

Aoki, T ;

Ohashi, T ;

Matsumoto, T ;

Sato, M .

ANNALS OF BIOMEDICAL ENGINEERING, 1997, 25 (03) :581-587

[4]

Badir S, PRENATAL DIAGNOSIS

[5] Assessment of the in vivo biomechanical properties of the human uterine cervix in pregnancy using the aspiration test A feasibility study [J].

Bauer, Margit ;

Mazza, Edoardo ;

Jabareen, Mahmood ;

Sultan, Leila ;

Bajka, Michael ;

Lang, Uwe ;

Zimmermann, Roland ;

Holzapfel, Gerhard A. .

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2009, 144 :S77-S81

[6] Gestational age at cervical length measurement and incidence of preterm birth [J].

Berghella, Vincenzo ;

Roman, Amanda ;

Daskalakis, Constantine ;

Ness, Amen ;

Baxter, Jason K. .

OBSTETRICS AND GYNECOLOGY, 2007, 110 (02) :311-317

[7] Beyond cervical length: emerging technologies for assessing the pregnant cervix [J].

Feltovich, Helen ;

Hall, Timothy J. ;

Berghella, Vincenzo .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2012, 207 (05) :345-354

[8] Electrical impedance spectroscopy of the cervix in non-pregnant and pregnant women [J].

Gandhi, Saurabh V. ;

Walker, Dawn ;

Milnes, Pete ;

Mukherjee, Soma ;

Brown, Brian H. ;

Anumba, Dilly O. C. .

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2006, 129 (02) :145-149

[9]

Hollenstein M., 2009, PAMM, V9, DOI [10.1002/pamm.200910022, DOI 10.1002/PAMM.200910022]

[10]

Hollenstein M., 2012, COMP MOD BIOM NAN MA

← 1 2 3 →