Neoadjuvant Chemotherapy in the Treatment of Breast Cancer

被引：62

作者：

Redden, Meredith H. ^{[1
]}

Fuhrman, George M. ^{[2
]}

机构：

[1] Atlanta Med Ctr, Atlanta, GA 30312 USA

[2] Ochsner Clin Fdn, Dept Surg, New Orleans, LA 70121 USA

来源：

SURGICAL CLINICS OF NORTH AMERICA | 2013年 / 93卷 / 02期

关键词：

Neoadjuvant chemotherapy; Trastuzumab; Nodal disease; Breast cancer; SURGICAL ADJUVANT BREAST; PREOPERATIVE CHEMOTHERAPY; MAMMOGRAPHY; MANAGEMENT; CONSERVATION; THERAPY; WOMEN; MRI;

D O I：

10.1016/j.suc.2013.01.006

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Randomized prospective trials have demonstrated that patients with early-stage breast cancer preferring breast conservation can benefit from neoadjuvant chemotherapy, achieving about a 25% complete and greater than 80% partial pathologic response. These responses do not translate into a survival advantage. For earlier stage patients, neoadjuvant chemotherapy's primary advantage is the ability to increase the use of breast conservation. Patients who opt for neoadjuvant chemotherapy should have a clinical and radiographic assessment of the axilla. The inability to predict the extent and pattern of response to chemotherapy requires that surgeons monitor patient response during neoadjuvant chemotherapy to provide optimal surgical planning.

引用

页码：493 / +

页数：8

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