New dimensions in cell migration

被引:195
作者
Friedl, Peter [1 ,2 ]
Sahai, Erik [3 ]
Weiss, Stephen [4 ]
Yamada, Kenneth M. [5 ]
机构
[1] Radboud Univ Nijmegen, Med Ctr, NL-6500 HC Nijmegen, Netherlands
[2] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[3] Canc Res UK, London Res Inst, London WC2A 3LY, England
[4] Univ Michigan, Ann Arbor, MI 48109 USA
[5] Natl Inst Dent & Craniofacial Res, Lab Cell & Dev Biol, NIH, Bethesda, MD 20892 USA
关键词
EXTRACELLULAR-MATRIX; LEUKOCYTE MIGRATION; CANCER; INVASION; COLLAGEN; MORPHOGENESIS; PLASTICITY;
D O I
10.1038/nrm3459
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Studies of cell migration in three-dimensional (3D) cell culture systems and in vivo have revealed several differences when compared with cell migration in two dimensions, including their morphology and mechanical and signalling control. Here, researchers assess the contribution of 3D models to our understanding of cell migration, both in terms of the mechanisms used to drive single cell and collective cell migration and how migrating cells respond to a changing environment in vivo.
引用
收藏
页码:743 / 747
页数:5
相关论文
共 30 条
[1]   Stress and matrix-responsive cytoskeletal remodeling in fibroblasts [J].
Abbott, Rosalyn D. ;
Koptiuch, Cathryn ;
Iatridis, James C. ;
Howe, Alan K. ;
Badger, Gary J. ;
Langevin, Helene M. .
JOURNAL OF CELLULAR PHYSIOLOGY, 2013, 228 (01) :50-57
[2]   Biomechanical and biochemical characteristics of a human fibroblast-produced and remodeled matrix [J].
Ahlfors, Jan-Eric W. ;
Billiar, Kristen L. .
BIOMATERIALS, 2007, 28 (13) :2183-2191
[3]   Cancer invasion and resistance: interconnected processes of disease progression and therapy failure [J].
Alexander, Stephanie ;
Friedl, Peter .
TRENDS IN MOLECULAR MEDICINE, 2012, 18 (01) :13-26
[4]   Dynamic imaging of cancer growth and invasion: a modified skin-fold chamber model [J].
Alexander, Stephanie ;
Koehl, Gudrun E. ;
Hirschberg, Markus ;
Geissler, Edward K. ;
Friedl, Peter .
HISTOCHEMISTRY AND CELL BIOLOGY, 2008, 130 (06) :1147-1154
[5]   Collagen Oligomers Modulate Physical and Biological Properties of Three-Dimensional Self-Assembled Matrices [J].
Bailey, J. L. ;
Critser, P. J. ;
Whittington, C. ;
Kuske, J. L. ;
Yoder, M. C. ;
Voytik-Harbin, S. L. .
BIOPOLYMERS, 2011, 95 (02) :77-93
[6]   Deconstructing the third dimension - how 3D culture microenvironments alter cellular cues [J].
Baker, Brendon M. ;
Chen, Christopher S. .
JOURNAL OF CELL SCIENCE, 2012, 125 (13) :3015-3024
[7]   Physical confinement alters tumor cell adhesion and migration phenotypes [J].
Balzer, Eric M. ;
Tong, Ziqiu ;
Paul, Colin D. ;
Hung, Wei-Chien ;
Stroka, Kimberly M. ;
Boggs, Amanda E. ;
Martin, Stuart S. ;
Konstantopoulos, Konstantinos .
FASEB JOURNAL, 2012, 26 (10) :4045-4056
[8]   A pericellular collagenase directs the 3-dimensional development of white adipose tissue [J].
Chun, Tae-Hwa ;
Hotary, Kevin B. ;
Sabeh, Farideh ;
Saltiel, Alan R. ;
Allen, Edward D. ;
Weiss, Stephen J. .
CELL, 2006, 125 (03) :577-591
[9]   Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma [J].
Conklin, Matthew W. ;
Eickhoff, Jens C. ;
Riching, Kristin M. ;
Pehlke, Carolyn A. ;
Eliceiri, Kevin W. ;
Provenzano, Paolo P. ;
Friedl, Andreas ;
Keely, Patricia J. .
AMERICAN JOURNAL OF PATHOLOGY, 2011, 178 (03) :1221-1232
[10]   Balancing forces: architectural control of mechanotransduction [J].
DuFort, Christopher C. ;
Paszek, Matthew J. ;
Weaver, Valerie M. .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2011, 12 (05) :308-319