10000 times volume reduction for fluorescence correlation spectroscopy using nano-antennas

被引：34

作者：

Estrada, Laura C. ^{[1
,4
]}

Aramendia, Pedro F. ^{[2
,3
,4
]}

Martinez, Oscar E. ^{[1
,4
]}

机构：

[1] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Fis, RA-1428 Buenos Aires, DF, Argentina

[2] Univ Buenos Aires, INQUIMAE, RA-1428 Buenos Aires, DF, Argentina

[3] Univ Buenos Aires, Dept Quim Inorgan Analyt & Quim Fis, Fac Ciencias Exactas & Nat, RA-1428 Buenos Aires, DF, Argentina

[4] Consejo Nacl Invest Cient & Tecn, RA-1033 Buenos Aires, DF, Argentina

来源：

OPTICS EXPRESS | 2008年 / 16卷 / 25期

关键词：

D O I：

10.1364/OE.16.020597

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We present an experimental and theoretical study of a new scheme for Near-Field Fluorescence Correlation Spectroscopy that, using the field enhancement by optical nanoantennas, allows the reduction of the observation volume 4 orders of magnitude below the diffraction limit. This reduction can be used in two different ways: to increase the sample concentration and to improve the spatial resolution of the dynamics under study. Our experimental results using individual gold nanoparticles and a 150 mu M Rose Bengal solution in glycerol confirm the volume reduction. (C) 2008 Optical Society of America

引用

页码：20597 / 20602

页数：6

共 23 条

[11] Feasibility of molecular-resolution fluorescence near-field microscopy using multi-photon absorption and field enhancement near a sharp tip [J].