10000 times volume reduction for fluorescence correlation spectroscopy using nano-antennas

被引：34
作者：
Estrada, Laura C. [1 ,4 ]
Aramendia, Pedro F. [2 ,3 ,4 ]
Martinez, Oscar E. [1 ,4 ]
机构：
[1] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Fis, RA-1428 Buenos Aires, DF, Argentina
[2] Univ Buenos Aires, INQUIMAE, RA-1428 Buenos Aires, DF, Argentina
[3] Univ Buenos Aires, Dept Quim Inorgan Analyt & Quim Fis, Fac Ciencias Exactas & Nat, RA-1428 Buenos Aires, DF, Argentina
[4] Consejo Nacl Invest Cient & Tecn, RA-1033 Buenos Aires, DF, Argentina
来源：
OPTICS EXPRESS | 2008年 / 16卷 / 25期
关键词：
D O I：
10.1364/OE.16.020597
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
We present an experimental and theoretical study of a new scheme for Near-Field Fluorescence Correlation Spectroscopy that, using the field enhancement by optical nanoantennas, allows the reduction of the observation volume 4 orders of magnitude below the diffraction limit. This reduction can be used in two different ways: to increase the sample concentration and to improve the spatial resolution of the dynamics under study. Our experimental results using individual gold nanoparticles and a 150 mu M Rose Bengal solution in glycerol confirm the volume reduction. (C) 2008 Optical Society of America
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页码：20597 / 20602
页数：6
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