Bacterial Lipopolysaccharides in Plant and Mammalian Innate Immunity

被引:15
作者
De Castro, Cristina [1 ]
Holst, Otto [2 ]
Lanzetta, Rosa [1 ]
Parrilli, Michelangelo [1 ]
Molinaro, Antonio [1 ]
机构
[1] Univ Naples Federico II, Dept Chem Sci, I-80126 Naples, Italy
[2] Leibniz Ctr Med & Biosci, Res Ctr Borstel, Div Struct Biochem, Borstel, Germany
关键词
Endotoxin; innate immunity; lipid A; LPS; PAMP; PRR; RECOGNITION; MODULATION;
D O I
10.2174/092986612802762714
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This mini-review gives a structural view on the lipopolysaccharides (LPSs), the endotoxin from Gram negative bacteria, paying attention on the features that are relevant for their activity as elicitors of the innate immune system of humans, animals and plants.
引用
收藏
页码:1040 / 1044
页数:5
相关论文
共 25 条
[1]   Pathogen recognition and innate immunity [J].
Akira, S ;
Uematsu, S ;
Takeuchi, O .
CELL, 2006, 124 (04) :783-801
[2]   Structure-dependent modulation of a pathogen response in plants by synthetic O-antigen polysaccharides [J].
Bedini, E ;
De Castro, C ;
Erbs, G ;
Mangoni, L ;
Dow, JM ;
Newman, MA ;
Parrilli, M ;
Unverzagt, C .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (08) :2414-2416
[3]   Innate immune sensing and its roots: the story of endotoxin [J].
Beutler, B ;
Rietschel, ET .
NATURE REVIEWS IMMUNOLOGY, 2003, 3 (02) :169-176
[4]   The Structural Biology of Toll-like Receptors [J].
Botos, Istvan ;
Segal, David M. ;
Davies, David R. .
STRUCTURE, 2011, 19 (04) :447-459
[5]   E5531, A PURE ENDOTOXIN ANTAGONIST OF HIGH POTENCY [J].
CHRIST, WJ ;
ASANO, O ;
ROBIDOUX, ALC ;
PEREZ, M ;
WANG, YA ;
DUBUC, GR ;
GAVIN, WE ;
HAWKINS, LD ;
MCGUINNESS, PD ;
MULLARKEY, MA ;
LEWIS, MD ;
KISHI, Y ;
KAWATA, T ;
BRISTOL, JR ;
ROSE, JR ;
ROSSIGNOL, DP ;
KOBAYASHI, S ;
HISHINUMA, L ;
KIMURA, A ;
ASAKAWA, N ;
KATAYAMA, K ;
YAMATSU, I .
SCIENCE, 1995, 268 (5207) :80-83
[6]   The induction and modulation of plant defense responses by bacterial lipopolysaccharides [J].
Dow, M ;
Newman, MA ;
von Roepenak, E .
ANNUAL REVIEW OF PHYTOPATHOLOGY, 2000, 38 :241-+
[7]   Immunology - The shape of things to come [J].
Fitzgerald, Katherine A. ;
Golenbock, Douglas T. .
SCIENCE, 2007, 316 (5831) :1574-1576
[8]   Innate immune recognition [J].
Janeway, CA ;
Medzhitov, R .
ANNUAL REVIEW OF IMMUNOLOGY, 2002, 20 :197-216
[9]   The plant immune system [J].
Jones, Jonathan D. G. ;
Dangl, Jeffery L. .
NATURE, 2006, 444 (7117) :323-329
[10]  
KUHN HM, 1988, FEMS MICROBIOL LETT, V54, P195, DOI 10.1016/0378-1097(88)90002-X