Interaction of cyanine dyes with nucleic acids.: XII.: β-substituted carbocyanines as possible fluorescent probes for nucleic acids detection.

被引：26

作者：

Yarmoluk, SM

Kovalska, VB

Lukashov, SS

Slominskii, YL

机构：

[1] Natl Acad Sci Ukraine, Inst Mol Biol & Genet, UA-252143 Kiev, Ukraine

[2] Natl Acad Sci Ukraine, Inst Organ Chem, UA-253660 Kiev, Ukraine

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1999年 / 9卷 / 12期

关键词：

D O I：

10.1016/S0960-894X(99)00253-X

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Results of investigations of fluorescent properties of a P-substituted carbocyanine and its complexes with nucleic acids in comparison with those for the unsubstituted dye are presented. Carbocyanine substituted in polymethine chain has shown promising properties for use as a fluorescent probe in homogeneous systems of nucleic acids detection. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：1677 / 1678

页数：2

共 9 条

[1]

CONNS HJ, 1977, BIOL STAINS, P368

[2]

Hamer F. M., 1964, CYANINE DYES RELATED, VXVIII, P790

[3]

HAUGHLAND RP, 1996, MOL PROBES HDB FLUOR, P680

[4]

SARGENT PB, 1994, NEUROIMAGE, V1, P228