Inhibition of plasma IL-6 in addition to maintenance of an efficacious trough level of infliximab associated with clinical remission in patients with rheumatoid arthritis: analysis of the RISING Study

被引:19
|
作者
Takeuchi, Tsutomu [1 ]
Miyasaka, Nobuyuki [2 ]
Tatsuki, Yoshihiko [3 ]
Yano, Toshiro [3 ]
Yoshinari, Toru [3 ]
Abe, Tohru [4 ]
Koike, Takao [5 ]
机构
[1] Keio Univ, Div Rheumatol, Dept Internal Med, Sch Med,Shinjuku Ku, Tokyo 1608582, Japan
[2] Tokyo Med & Dent Univ, Dept Med & Rheumatol, Grad Sch, Bunkyo Ku, Tokyo, Japan
[3] Mitsubishi Tanabe Pharma Corp, Osaka, Japan
[4] Saitama Med Univ, Saitama Med Ctr, Kawagoe, Saitama, Japan
[5] Sapporo Med Ctr NTT EC, Chuo Ku, Sapporo, Hokkaido, Japan
关键词
TNF-ALPHA THERAPY; DISEASE-ACTIVITY; DOSE-ESCALATION;
D O I
10.1136/annrheumdis-2011-201069
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1583 / 1585
页数:3
相关论文
共 1 条
  • [1] High titers of both rheumatoid factor and anti-CCP antibodies at baseline in patients with rheumatoid arthritis are associated with increased circulating baseline TNF level, low drug levels, and reduced clinical responses: a post hoc analysis of the RISING study
    Takeuchi, Tsutomu
    Miyasaka, Nobuyuki
    Inui, Takashi
    Yano, Toshiro
    Yoshinari, Toru
    Abe, Tohru
    Koike, Takao
    ARTHRITIS RESEARCH & THERAPY, 2017, 19