Microarray analysis of differentially expressed genes in the liver between Bai'er layers and broilers

被引:1
作者
Wang, Q. -G. [1 ,2 ,4 ]
Zhang, H. -F. [1 ,2 ,3 ]
Wang, S. -Z. [1 ,2 ,3 ]
Gao, G. L. [1 ,2 ,4 ]
Leng, L. [1 ,2 ,3 ]
Na, W. [1 ,2 ,3 ]
Li, H. [1 ,2 ,3 ]
机构
[1] Minist Agr, Key Lab Chicken Genet & Breeding, Harbin, Peoples R China
[2] Educ Dept Heilongjiang Prov, Key Lab Anim Genet Breeding & Reprod, Harbin, Peoples R China
[3] Northeast Agr Univ, Coll Anim Sci & Technol, Harbin, Peoples R China
[4] Chongqing Acad Anim Sci, Chongqing, Peoples R China
基金
中国国家自然科学基金;
关键词
Chicken; Gene expression profile; Liver; ADIPOSE-TISSUE; ADIPOGENESIS;
D O I
10.4238/2015.March.31.19
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this study, we profiled gene expression in chicken liver and screened differentially expressed genes in the Bai'er layers and fat line broilers. Birds were derived from the 14th generation of Northeast Agricultural University fat broiler lines and Bai'er layers. Chicken genome arrays were used to screen differentially expressed genes in liver tissue from the Bai'er layers and fat line broilers. We screened 671 differentially expressed genes between broilers and layers at the ages of 2 and 4 weeks. We observed enrichment of a series of significant pathways, including the mitogen-activated protein kinase signaling pathway, cell cycle, mammalian target of rapamycin signaling pathway, and p53 signaling pathway. At 2 and 4 weeks, 94 shared differentially expressed genes were observed. We speculated that these genes regulate chicken lipid metabolism.
引用
收藏
页码:2885 / 2889
页数:5
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