In vitro bioactivity of a biocomposite fabricated from HA and Ti powders by powder metallurgy method

被引:204
作者
Ning, CQ [1 ]
Zhou, Y [1 ]
机构
[1] Harbin Inst Technol, Sch Mat Sci & Engn, Harbin 150001, Peoples R China
关键词
biocomposite; in vitro; bioactivity; simulated body fluid; apatite;
D O I
10.1016/S0142-9612(01)00419-7
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Traditionally, hydroxyapatite was used as a coating material on titanium substrate by various techniques. In the present work, a biocomposite was successfully fabricated from hydroxyapatite and titanium powders by powder metallurgy method. Bioactivity of the composite in a simulated body fluid (SBF) was investigated. Main crystal phases of the as-fabricated composite are found to be Ti2O, CaTiO3, CaO, alpha-Ti and a TiP-like phase. When the composite is immersed in the simulated body fluid for a certain time, a poor-crystallized, calcium-deficient, carbonate-containing apatite film will form on the surface of the composite. The time required to induce apatite nucleation is within 2 h. In addition, the apatite is also incorporated with a little magnesium and chlorine element. It is found that Ti2O has the ability to induce the formation of bone-like apatite in the SBF. And a dissolve of the CaO phase could also provide favorable conditions for the apatite formation, by forming open pores on the surface of the composite and increasing the degree of supersaturation of the SBF with respect to the apatite. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:2909 / 2915
页数:7
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