Pacritinib Targets IRAK1 and Shows Synergy with HDAC and BET Inhibitors in Acute Myeloid Leukemia

被引:4
作者
Puri, Alka [1 ]
Mahmood, Shawn [1 ]
Maertens, Bernadette [1 ]
Davare, Monika [2 ]
Kurtz, Stephen E. [1 ]
Tognon, Cristina E. [1 ,3 ]
Eden, Christopher O. [1 ]
Elferich, Johannes [4 ]
Shinde, Ujwal [4 ]
Druker, Brian J. [1 ,3 ]
Singer, Jack W. [5 ]
Agarwal, Anupriya [1 ]
机构
[1] Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR USA
[2] Oregon Hlth & Sci Univ, Pape Pediat Res Inst, Dept Pediat, Portland, OR USA
[3] Howard Hughes Med Inst, Portland, OR USA
[4] Oregon Hlth & Sci Univ, Dept Biochem & Mol Biol, Portland, OR USA
[5] CTI BioPharma Corp, Seattle, WA USA
关键词
D O I
10.1182/blood.V128.22.3514.3514
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
3514
引用
收藏
页数:5
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