Plasmablastic lymphoma in pediatric patients: clinicopathologic study of three cases

被引:18
作者
Pather, Sugeshnee [1 ]
MacKinnon, Diane [2 ]
Padayachee, Rushen S.
机构
[1] Univ Witwatersrand, Fac Hlth Sci, Chris Hani Baragwanath Acad Hosp, Natl Hlth Lab Serv,Dept Anat Pathol, Johannesburg, South Africa
[2] Univ Witwatersrand, Chris Hani Baragwanath Acad Hosp, Dept Paediat Haematol & Oncol, Johannesburg, South Africa
关键词
Plasmablastic lymphoma; Pediatric; HIV infection; ORAL-CAVITY; NEGATIVE PATIENT; DIFFERENTIATION; INFECTION; DISEASE;
D O I
10.1016/j.anndiagpath.2012.08.005
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Plasmablastic lymphoma (PBL) is an aggressive high grade non-Hodgkin lymphoma which occurs predominantly in adult patients who are concomitantly afflicted with HIV infection. In contrast to several reports and studies of PBL in adult patients, PBL has very rarely been reported in pediatric patients. This article hereby provides collaborative clinicopathologic information of de novo PBL diagnosed in 3 pediatric patients with concomitant HIV infection. Cognizance of this rare tumor in the pediatric population coupled with antiretroviral therapy and prompt initiation of multimodality treatment may, in the future, facilitate improved outcome in pediatric patients with PBL. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码:80 / 84
页数:5
相关论文
共 32 条
[1]  
[Anonymous], 2008, WHO Classification of Tumours of Haematopoietic and Lymphoid tissues, V4th, P200
[2]  
[Anonymous], WHO CLASSIFICATION T
[3]  
[Anonymous], 2008, WHO CLASSIFICATION T
[4]   MALIGNANT-LYMPHOMA OF PLASMABLASTIC IDENTITY - NEOPLASM WITH BOTH IMMUNOBLASTIC AND PLASMA CELLULAR FEATURES [J].
BANKS, PM ;
KELLER, RH ;
LI, CY ;
WHITE, WL .
AMERICAN JOURNAL OF MEDICINE, 1978, 64 (05) :906-909
[5]  
Brown R S, 1998, Clin Oncol (R Coll Radiol), V10, P327, DOI 10.1016/S0936-6555(98)80089-7
[6]   AIDS-related plasmablastic lymphomas of the oral cavity and jaws: A diagnostic dilemma [J].
Carbone, A ;
Gaidano, G ;
Gloghini, A ;
Ferlito, A ;
Rinaldo, A ;
Stein, H .
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 1999, 108 (01) :95-99
[7]  
Cathomas G, 1998, MODERN PATHOL, V11, P415
[8]   Vulvar plasmablastic lymphoma in a HIV-positive child: a novel extraoral localisation [J].
Chabay, P. ;
De Matteo, E. ;
Lorenzetti, M. ;
Gutierrez, M. ;
Narbaitz, M. ;
Aversa, L. ;
Preciado, M. V. .
JOURNAL OF CLINICAL PATHOLOGY, 2009, 62 (07) :644-646
[9]  
Chan JKC, 2007, DIAGNOSTIC HISTOPATH, V2, P1139
[10]   Plasmablastic lymphoma in HIV+ patients: an expanding spectrum [J].
Chetty, R ;
Hlatswayo, N ;
Muc, R ;
Sabaratnam, R ;
Gatter, K .
HISTOPATHOLOGY, 2003, 42 (06) :605-609