Type 1 diabetes mellitus and epilepsia partialis continua in a 6-year-old boy with elevated anti-GAD65 antibodies

被引：44
作者：
Olson, JA
Olson, DM
Sandborg, C
Alexander, S
Buckingham, B
机构：
[1] Lucile Packard Childrens Hosp Stanford, Dept Pediat, Div Endocrinol, Stanford, CA USA
[2] Lucile Packard Childrens Hosp Stanford, Div Neurol, Stanford, CA USA
[3] Lucile Packard Childrens Hosp Stanford, Div Rheumatol, Stanford, CA USA
[4] Lucile Packard Childrens Hosp Stanford, Div Nephrol, Stanford, CA USA
来源：
PEDIATRICS | 2002年 / 109卷 / 03期
关键词：
GAD65; antibody; type 1 diabetes mellitus; Rasmussen encephalitis; seizure; plasmapheresis; autoimmunity;
D O I：
10.1542/peds.109.3.e50
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
A 6-year-old boy presented with epilepsia partialis continua 6 months after diagnosis of type 1 diabetes. Anti-glutamic acid decarboxylase 65 antibodies were found in his serum and cerebrospinal fluid. Antiepileptic agents did not improve his seizures. High-dose steroids, plasmapheresis, and intravenous immunoglobulin resulted in decreased anti-glutamic acid decarboxylase 65 antibody levels and resolution of his seizures.
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