Ketone Formation via Mild Nickel-Catalyzed Reductive Coupling of Alkyl Halides with Aryl Acid Chlorides

被引：129

作者：

Wu, Fan ^{[1
]}

Lu, Wenbin ^{[1
]}

Qian, Qun ^{[1
]}

Ren, Qinghua ^{[1
]}

Gong, Hegui ^{[1
]}

机构：

[1] Shanghai Univ, Dept Chem, Shanghai 200444, Peoples R China

来源：

ORGANIC LETTERS | 2012年 / 14卷 / 12期

关键词：

EFFICIENT SYNTHESIS; ALLYLIC ACETATES; CROSS-COUPLINGS; ACYL CHLORIDES; DIARYL KETONES; BROMIDES; ELECTROPHILES; REAGENTS; COBALT; ELECTROSYNTHESIS;

D O I：

10.1021/ol3011198

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The present work highlights unprecedented Ni-catalyzed reductive coupling of unactivated alkyl iodides with aryl acid chlorides to efficiently generate alkyl aryl ketones under mild conditions.

引用

页码：3044 / 3047

页数：4

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