Synthesis and resolution of 2,2-dimethyl-1,3-diphenyl-1,3-propanediol, a new C2-symmetric and conformationally rigid acyclic diol

被引：9

作者：

Bhowmick, KC ^{[1
]}

Prasad, KRK ^{[1
]}

Joshi, NN ^{[1
]}

机构：

[1] Natl Chem Lab, Div Organ Synth, Pune 411008, Maharashtra, India

来源：

TETRAHEDRON-ASYMMETRY | 2002年 / 13卷 / 08期

关键词：

D O I：

10.1016/S0957-4166(02)00185-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Diastereomerically pure (+)- and (-)-2,2-dimethyl-1,3-diplienyl-1,3-propanediols were synthesized starting from diethyl malonate and resolved through diesters of (-)-camphanic acid and also N-carbethoxy-L-proline. The absolute configuration of the (-)-enantiomer was established by X-ray crystallography. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：851 / 855

页数：5

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