Synthesis of new derivatives of pyrimido[5,4-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazine and their enzyme inhibitory activity assessment on soybean 15-lipoxygenase

被引：22

作者：

Bakavoli, Mehdi ^{[1
]}

Seyedi, Seyed Mohammad ^{[1
]}

Shiri, Ali ^{[1
]}

Saberi, Sattar ^{[1
]}

Gholami, Mahmoud ^{[1
]}

Sadeghian, Hamid ^{[2
]}

机构：

[1] Ferdowsi Univ Mashhad, Sch Sci, Dept Chem, Mashhad 917751436, Iran

[2] Mashhad Univ Med Sci, Dept Lab Sci, Sch Paramed Sci, Mashhad 9185763788, Iran

来源：

JOURNAL OF CHEMICAL RESEARCH | 2013年 / 01期

关键词：

pyrimidotriazolothiadiazines; triazoles; annulated pyrimidines; 15-lipoxygenase inhibitor; heterocyclisation; BENZODIAZEPINE-RECEPTOR LIGANDS; HETEROCYCLIC-COMPOUNDS; AGENTS; HYDRAZONES;

D O I：

10.3184/174751912X13549029453945

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis of new derivatives of pyrimido[5,4-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazine is described. These derivatives have a wide range of medicinal applications. Their inhibitory activity against the enzyme 15-lipoxygenase was also investigated.

引用

页码：48 / 50

页数：3

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