Cryptococcosis in Solid Organ Transplant Recipients: Current State of the Science

被引：150

作者：

Singh, Nina ^{[1
]}

Dromer, Francoise ^{[3
]}

Perfect, John R. ^{[2
]}

Lortholary, Olivier ^{[3
,4
]}

机构：

[1] Univ Pittsburgh, Infect Dis Sect 111E, VA Med Ctr, Pittsburgh, PA 15240 USA

[2] Duke Univ, Durham, NC USA

[3] Natl Reference Ctr Mycoses & Antifungals, Inst Pasteur, Mol Mycol Unit, Paris, France

[4] Univ Paris 05, Ctr Infectiol Necker Pasteur, Hop Necker Enfants Malad, Paris, France

来源：

CLINICAL INFECTIOUS DISEASES | 2008年 / 47卷 / 10期

关键词：

D O I：

10.1086/592690

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Cryptococcosis remains a significant opportunistic infection in solid organ transplant recipients. Disease presentation and outcomes may be affected by, among other factors, the use of calcineurin inhibitor immunosuppressive agents. It is being increasingly recognized that rapid reversal of immunosuppression in transplant recipients treated for cryptococcosis incurs the risk of immune reconstitution inflammatory syndrome, which resembles worsening disease or relapse. This review summarizes the current state of knowledge regarding cryptococcosis in transplant recipients and highlights areas where future investigations are needed to further optimize outcomes for these patients.

引用

页码：1321 / 1327

页数：7

共 64 条

[1]

BADDLEY JW, 2008, EUR J CLIN MICROBIOL

[2]

BEYT BE, 1978, NEW ENGL J MED, V298, P825, DOI 10.1056/NEJM197804132981506

[3] Cryptococcus neoformans isolates from transplant recipients are not selected for resistance to calcineurin inhibitors by current immunosuppressive regimens [J].

Blankenship, JR ;

Singh, N ;

Alexander, BD ;

Heitman, J .

JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (01) :464-467

[4] Testing electronic structure methods for describing intermolecular H ••• H interactions in supramolecular chemistry [J].

Casadesús, R ;

Moreno, M ;

González-Lafont, A ;

Lluch, JM ;

Repasky, MP .

JOURNAL OF COMPUTATIONAL CHEMISTRY, 2004, 25 (01) :99-105

[5] Cryptococcal Neuroradiological Lesions Correlate with Severity during Cryptococcal Meningoencephalitis in HIV-Positive Patients in the HAART Era [J].

Charlier, Caroline ;

Dromer, Francoise ;

Leveque, Christophe ;

Chartier, Loic ;

Cordoliani, Yves-Sebastien ;

Fontanet, Arnaud ;

Launay, Odile ;

Lortholary, Olivier .

PLOS ONE, 2008, 3 (04)

[6] Clinical and radiologic factors associated with pulmonary nodule etiology in organ transplant recipients [J].

Copp, D. H. ;

Godwin, J. D. ;

Kirby, K. A. ;

Limaye, A. P. .

AMERICAN JOURNAL OF TRANSPLANTATION, 2006, 6 (11) :2759-2764

[7] Predominant Th1 cell infiltration in acute rejection episodes of human kidney grafts [J].

DElios, M ;

Josien, R ;

Manghetti, M ;

Amedei, A ;

deCarli, M ;

Cuturi, MC ;

Blancho, G ;

Buzelin, F ;

delPrete, G ;

Soulillou, JP .

KIDNEY INTERNATIONAL, 1997, 51 (06) :1876-1884

[8] PROGNOSTIC FACTORS IN CRYPTOCOCCAL MENINGITIS - STUDY IN 111 CASES [J].

DIAMOND, RD ;

BENNETT, JE .

ANNALS OF INTERNAL MEDICINE, 1974, 80 (02) :176-181

[9]

Dilhuydy Marie-Sarah, 2007, Br J Haematol, V137, P490, DOI 10.1111/j.1365-2141.2007.06580.x

[10] Epidemiology of HIV-associated cryptococcosis in France (1985-2001):: comparison of the pre- and post-HAART eras [J].

Dromer, F ;

Mathoulin-Pélissier, S ;

Fontanet, A ;

Ronin, O ;

Dupont, B ;

Lortholary, O .

AIDS, 2004, 18 (03) :555-562

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