Synthesis of 2([methyl-5-[(E)-2-aryl-1-ethenyl]-4-isoxazolyl]imino)-1,3-thiazolan-4-ones and their Mannich bases

被引：5

作者：

Rajanarendar, E. ^{[1
]}

Ramesh, P. ^{[1
]}

Rao, E. Kalyan ^{[1
]}

Reddy, A. Siva Rami ^{[1
]}

机构：

[1] Kakatiya Univ, Dept Chem, Warangal 506009, Andhra Pradesh, India

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2008年 / 183卷 / 10期

关键词：

isoxazolyl chloroacetamides; isoxazolyl thiazolidinones; Mannich bases;

D O I：

10.1080/10426500801967856

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Isoxazolyl chloroacetamides (2) were obtained from 4-amino-3-methyl-5-styrylisoxazoles (1) on reaction with chloroacetyl chloride. Cyclocondensation of 2 with NH4SCN yielded 2([-methyl-5-(E)-2-aryl-1-ethenyl]-4-isoxazolylimino)-1,3-thiazolan-4-ones(3). Mannich reaction of 3 with formaldehyde and secondary amines gave isoxazolyl thiazolidinone Mannich bases (4 and 5).

引用

页码：2555 / 2564

页数：10

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