Fabrication of Human IgG Sensors Based on Porous Silicon Interferometer Containing Bragg Structures

被引：6

作者：

Cho, Bomin ^{[1
]}

Lee, Bo-Yeon ^{[1
]}

Kim, Hee-Cheol ^{[1
]}

Woo, Hee-Gweon ^{[2
]}

Sohn, Honglae ^{[1
]}

机构：

[1] Chosun Univ, Dept Chem, Kwangju 501759, South Korea

[2] Chonnam Natl Univ, Dept Chem, Kwangju 500757, South Korea

来源：

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | 2012年 / 12卷 / 05期

关键词：

Biosensor; Protein A; Reflectivity; DBR PSi; Human Immunoglobin G; BIOSENSOR; LAYERS; SIO2;

D O I：

10.1166/jnn.2012.5921

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simply modified biosensor based on protein A-modified distributed Bragg reflectors (DBR) porous silicon (PSI) chip for the detection of human immunoglobin G (IgG) are developed. The fabrication, optical characterization, and surface derivatization of DBR PSI are investigated. The sensor system studied consist of multi-layer of porous silicon modified with protein-A. The sensor is operated by the measurement of the reflection peak in the white light reflection spectrum. Molecular binding is detected as a shift in wavelength of reflection peaks.

引用

页码：4159 / 4162

页数：4

共 22 条

[1] Fiber-optic evanescent wave biosensor for the detection of oligonucleotides [J].