New and Emerging Risk Factors for Coronary Heart Disease

被引：71

作者：

Akhabue, Ehimare ^{[1
]}

Thiboutot, Jeffrey ^{[1
]}

Cheng, Jeh-wei ^{[2
]}

Vittorio, Timothy J. ^{[3
]}

Christodoulidis, Georgios ^{[4
]}

Grady, Kathleen M. ^{[5
]}

Lerakis, Stamatios ^{[2
]}

Kosmas, Constantine E. ^{[6
]}

机构：

[1] Mt Sinai Sch Med, Dept Internal Med, New York, NY USA

[2] Emory Univ, Sch Med, Dept Med, Atlanta, GA USA

[3] St Francis Hosp, Ctr Heart, Div Cardiol, Ctr Adv Cardiac Therapeut, Roslyn, NY USA

[4] SUNY Stony Brook, Winthrop Univ Hosp, Dept Internal Med, Mineola, NY 11501 USA

[5] Cardiovasc Consultants Long Isl PC, New York, NY USA

[6] Mt Sinai Sch Med, Zena & Michael Wiener Cardiovasc Inst, New York, NY USA

来源：

AMERICAN JOURNAL OF THE MEDICAL SCIENCES | 2014年 / 347卷 / 02期

关键词：

Coronary heart disease; Coronary artery calcium score; C-reactive protein; Lipoprotein (a); Carotid intimal media thickness; C-REACTIVE PROTEIN; DENSITY-LIPOPROTEIN CHOLESTEROL; BEAM COMPUTED-TOMOGRAPHY; INTIMA-MEDIA THICKNESS; FUTURE CARDIOVASCULAR EVENTS; BREAST-CANCER PATIENTS; ARTERY CALCIUM SCORE; APOLIPOPROTEIN-A-I; MYOCARDIAL-INFARCTION; PHOSPHOLIPASE-A2; LEVELS;

D O I：

10.1097/MAJ.0b013e31828aab45

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Coronary heart disease (CHD) is one of the leading causes of death in the United States. Traditional risk factors such as family history, hypertension, hypercholesterolemia, diabetes mellitus and smoking cannot account for the entire risk for incident coronary events. Several other potential risk factors have been identified in an effort to improve risk assessment for CHD. This article reviews the current evidence on new and emerging risk factors for CHD and their current utility in screening, specifically focusing on coronary artery calcium score, C-reactive protein, lipoprotein (a), carotid intima-media thickness, homocysteine, lipoprotein-associated phospholipase A2, as well as high-density lipoprotein functionality.

引用

页码：151 / 158

页数：8

共 129 条

[1] Cardiovascular status in long-term survivors of Hodgkin's disease treated with chest radiotherapy [J].

Adams, MJ ;

Lipsitz, SR ;

Colan, SD ;

Tarbell, NJ ;

Treves, ST ;

Diller, L ;

Greenbaum, N ;

Mauch, P ;

Lipshultz, SE .

JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (15) :3139-3148

[2] Coronary Calcium Score and Prediction of All-Cause Mortality in Diabetes The Diabetes Heart Study [J].

Agarwal, Subhashish ;

Morgan, Timothy ;

Herrington, David M. ;

Xu, Jianzhao ;

Cox, Amanda J. ;

Freedman, Barry I. ;

Carr, J. Jeffrey ;

Bowden, Donald W. .

DIABETES CARE, 2011, 34 (05) :1219-1224

[3] QUANTIFICATION OF CORONARY-ARTERY CALCIUM USING ULTRAFAST COMPUTED-TOMOGRAPHY [J].

AGATSTON, AS ;

JANOWITZ, WR ;

HILDNER, FJ ;

ZUSMER, NR ;

VIAMONTE, M ;

DETRANO, R .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1990, 15 (04) :827-832

[4] Relation of Coronary Artery Calcium Score to Premature Coronary Artery Disease in Survivors >15 Years of Hodgkin's Lymphoma [J].

Andersen, Rune ;

Wethal, Torgeir ;

Gunther, Anne ;

Fossa, Alexander ;

Edvardsen, Thor ;

Fossa, Sophie D. ;

Kjekshus, John .

AMERICAN JOURNAL OF CARDIOLOGY, 2010, 105 (02) :149-152

[5] Treatment of asymptomatic adults with elevated coronary calcium scores with atorvastatin, vitamin C, and vitamin E - The St. Francis Heart Study Randomized Clinical Trial [J].

Arad, Y ;

Spadaro, LA ;

Roth, M ;

Newstein, D ;

Guerci, AD .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 46 (01) :166-172

[6] Coronary calcification, coronary disease risk factors, C-reactive protein, and atherosclerotic cardiovascular disease events - The St. Francis Heart Study [J].

Arad, Y ;

Goodman, KJ ;

Roth, M ;

Newstein, D ;

Guerci, AD .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 46 (01) :158-165

[7] Predictive value of electron beam computed tomography of the coronary arteries - 19-month follow-up of 1173 asymptomatic subjects [J].

Arad, Y ;

Spadaro, LA ;

Goodman, K ;

LledoPerez, A ;

Sherman, S ;

Lerner, C ;

Guerci, AD .

CIRCULATION, 1996, 93 (11) :1951-1953

[8] Effects of torcetrapib in patients at high risk for coronary events [J].

Barter, Philip J. ;

Caulfield, Mark ;

Eriksson, Mats ;

Grundy, Scott M. ;

Kastelein, John J. P. ;

Komajda, Michel ;

Lopez-Sendon, Jose ;

Mosca, Lori ;

Tardif, Jean-Claude ;

Waters, David D. ;

Shear, Charles L. ;

Revkin, James H. ;

Buhr, Kevin A. ;

Fisher, Marian R. ;

Tall, Alan R. ;

Brewer, Bryan .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (21) :2109-2122

[9] Consistency of Extended-Release Niacin/Laropiprant Effects on Lp(a), ApoB, non-HDL-C, Apo A1, and ApoB/ApoA1 Ratio Across Patient Subgroups [J].

Bays, Harold E. ;

Shah, Arvind ;

Lin, Jianxin ;

Sisk, Christine McCrary ;

Dong, Qian ;

Maccubbin, Darbie .

AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS, 2012, 12 (03) :197-206

[10] Effects of Statins on Progression of Carotid Atherosclerosis as Measured By Carotid Intimal-Medial Thickness: A Meta-Analysis of Randomized Controlled Trials [J].

Bedi, Updesh Singh ;

Singh, Mukesh ;

Singh, Param Puneet ;

Bhuriya, Rohit ;

Bahekar, Amol ;

Molnar, Janos ;

Khosla, Sandeep ;

Arora, Rohit .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS, 2010, 15 (03) :268-273

← 1 2 3 4 5 6 7 8 9 10 →