Biperiden and haloperidol plasma levels and extrapyramidal side effects in schizophrenic patients

被引：5
|
作者：
Meszaros, K
Lenzinger, E
Hornik, K
Schonbeck, G
Hatzinger, R
Langer, G
Sieghart, W
Aschauer, HN
机构：
[1] UNIV VIENNA, HOSP PSYCHIAT, DEPT GEN PSYCHIAT, VIENNA, AUSTRIA
[2] VIENNA UNIV ECON, DEPT STAT, VIENNA, AUSTRIA
[3] VIENNA TECH UNIV, INST STAT & WAHRSCHEINLICHKEITSTHEORIE, VIENNA, AUSTRIA
来源：
NEUROPSYCHOBIOLOGY | 1997年 / 36卷 / 02期
关键词：
biperiden plasma levels; haloperidol plasma levels; relation between dose and plasma levels; extrapyramidal side effects; chronic schizophrenia;
D O I：
10.1159/000119365
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Anticholinergic drugs such as biperiden are used for the treatment of extrapyramidal side effects (EPS) induced by neuroleptics such as haloperidol. The effects of biperiden and haloperidol plasma levels on EPS were studied in 29 chronically ill schizophrenics. The results show relationships between biperiden dose and biperiden plasma levels (BPL), and between BPL and haloperidol plasma levels (HPL). Neither BPL nor HPL seem to influence EPS.
引用
收藏
页码：69 / 72
页数：4
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