Primary Ewing Sarcoma of the Stomach - A Newly Described Entity

被引：21

作者：

Rafailidis, S. ^{[1
]}

Ballas, K. ^{[1
]}

Psarras, K. ^{[1
]}

Pavlidis, T. ^{[1
]}

Symeonidis, N. ^{[1
]}

Marakis, G. ^{[1
]}

Sakadamis, A. ^{[1
]}

机构：

[1] Aristotle Univ Thessaloniki, Propedeut Dept Surg 2, GR-54006 Thessaloniki, Greece

来源：

EUROPEAN SURGICAL RESEARCH | 2009年 / 42卷 / 01期

关键词：

Gastric cancer; Ewing sarcoma; Small round cell tumors; Primitive neuroectodermal tumors; PRIMITIVE NEUROECTODERMAL TUMOR; ROUND-CELL TUMORS; C-KIT; FAMILY; EXPRESSION; BIOLOGY; BONE;

D O I：

10.1159/000166166

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

The Ewing sarcoma family of tumors (ESFT) includes classic Ewing sarcoma of the bone, extraosseous or soft tissue Ewing sarcoma, Askin tumors of the chest wall, and peripheral primitive neuroectodermal tumors of the bone and soft tissues. They share a common neural histogenesis, tumor genetics and biology. The genetic hallmark of the ESFT is the presence of t(11; 22)(q24; q12), which creates the EWS/FLI1 fusion gene and results in the expression of a chimeric protein. Although Ewing tumors can occur at any age, the great majority are found in individuals less than 20 years of age. We herein report a case of gastric Ewing sarcoma in a 68-year-old male. This patient illustrates the second reported occurrence of primary Ewing sarcoma in the stomach and the first reported with the t(11; 22)(q24; q12) gene translocation. Copyright (c) 2008 S. Karger AG, Basel

引用

页码：17 / 20

页数：4

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