High resolution multicolor-banding:: a new technique for refined FISH analysis of human chromosomes

被引：161
作者：
Chudoba, I
Plesch, A
Lörch, T
Lemke, J
Claussen, U
Senger, G
机构：
[1] MetaSyst GMBH, D-68804 Altlussheim, Germany
[2] Inst Human Genet & Anthropol, Jena, Germany
[3] Praxis Med Genet, Regensburg, Germany
来源：
CYTOGENETICS AND CELL GENETICS | 1999年 / 84卷 / 3-4期
关键词：
D O I：
10.1159/000015245
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
A new multicolor-banding technique has been developed which allows the differentiation of chromosome region specific areas at the band level. This technique is based on the use of differently labeled overlapping microdissection libraries. The changing fluorescence intensity ratios along the chromosomes are used to assign different pseudo-colors to specific chromosome regions. The multicolor banding of human chromosome 5 is presented as an example.
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页码：156 / 160
页数：5
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