Succinic Acid Production in Fed-Batch Fermentation of Anaerobiospirillum succiniciproducens Using Glycerol as Carbon Source

被引：12

作者：

Bretz, Karlheinz ^{[1
]}

机构：

[1] Fraunhofer Inst Environm Safety & Energy Technol, Dept Proc Engn, D-46047 Oberhausen, Germany

来源：

CHEMICAL ENGINEERING & TECHNOLOGY | 2015年 / 38卷 / 09期

关键词：

Anaerobiospirillum succiniciproducens; Fed-batch fermentation; Glycerol; Succinic acid production; WHEY;

D O I：

10.1002/ceat.201500015

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Considering glycerol as an inexpensive alternative carbon source, the optimal glycerol concentration for succinic acid production with Anaerobiospirillum succiniciproducens was identified in shake-flask trials. The addition of a defined amount of glucose improved the growth and succinic acid productivity significantly. In fed-batch processes with glycerol as sole substrate, a maximum succinic acid concentration and product substrate yield were obtained. The addition of glucose led to a 2.5-fold increased succinic acid concentration whereas the product substrate yield remained nearly constant.

引用

页码：1659 / 1664

页数：6