PRECISION ONCOLOGY: MYTH OR REALITY?

被引:0
作者
Slavyanskaya, T. A. [1 ,2 ]
Salnikova, S., V [1 ,2 ]
机构
[1] Peoples Friendship Univ Russia, Moscow, Russia
[2] Inst Immunophysiol, Moscow, Russia
来源
BULLETIN OF RUSSIAN STATE MEDICAL UNIVERSITY | 2019年 / 02期
关键词
cancer; nonspecific immunotherapy; cytokine therapy; targeted therapy; monoclonal antibodies; immune checkpoints; cancer vaccines; gene therapy; nanotechnologies; precision medicine; T-CELLS; CANCER-IMMUNOTHERAPY; SUPPRESSOR-CELLS; THERAPY; NIVOLUMAB; NANOPARTICLES; CONTRIBUTES; ACTIVATION; IPILIMUMAB; RECEPTORS;
D O I
10.24075/brsmu.2019.018
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cancer incidence rates are growing at an alarming pace pressing for the development of innovative personalized approaches to treating this disease. The absence of clinical symptoms in the early stages delays the onset of adequate treatment. Traditional therapies are not always as effective as they should be and do not guarantee long-lasting relapse-free survival. Metastatic cancers pose a particular challenge to healthcare professionals. This review touches upon the immunologic mechanisms underlying the development of malignancies, talks about conventional and innovative therapeutic modalities, such as targeted, gene or specific immunotherapies, and analyzes the literature on the use of different approaches that form a basis for precision oncology.
引用
收藏
页码:5 / 14
页数:10
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