Agreement between Time-Domain and Spectral-Domain Optical Coherence Tomography in the Assessment of Macular Thickness in Patients with Idiopathic Macular Telangiectasia Type 2

被引:6
作者
Mathew, Raeba [1 ,2 ]
Sivaprasad, Sobha [1 ,2 ]
Florea, Daniela [1 ,2 ]
Leung, Irene [1 ,2 ]
Sallo, Ferenc [1 ,2 ]
Clemons, Traci [3 ]
Bird, Alan C. [1 ,3 ]
Peto, Tunde [1 ,2 ]
机构
[1] Moorfields Eye Hosp NHS Fdn Trust, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
[2] UCL Inst Ophthalmol, London EC1V 2PD, England
[3] EMMES Corp, Rockville, MD USA
关键词
Macular telangiectasia type 2a; Spectral-domain optical coherence tomography; Time-domain optical coherence tomography; Macular thickness; RETINAL THICKNESS; NORMAL EYES; STRATUS; INSTRUMENTS; CIRRUS; EDEMA;
D O I
10.1159/000353455
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To estimate the conversion factors to transpose macular thickness measurements on time-domain (TD) to various spectral-domain (SD) optical coherence tomography (OCT) machines in patients with macular telangiectasia type 2a (MacTel). Procedures: Macular scans on TD- and SD-OCT were performed on patients at the same visit. The retinal thickness values in various ETDRS subfields and macular volume were compared between different OCT machines. Results: The macular thickness and volume were significantly greater (p < 0.0001, r = 0.678-0.822) on SD-OCT. The mean differences in macular thickness between TD Stratus and SD-OCT by Spectralis, Cirrus and Topcon were 62, 41 and 20 mu m, respectively. The conversion factor of macular thickness from TD-OCT to Spectralis, Cirrus and Topcon were +65, +39 and +25 mu m, respectively. Conclusion and Message: The estimates of conversion of macular thickness from TD- to SD-OCT using simple mean differences between machines and those by linear regression were similar suggesting that the former may be used for the longitudinal follow-up of MacTel patients. (C) 2013 S. Karger AG, Basel
引用
收藏
页码:144 / 150
页数:7
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