Risk Factors for Disseminated Coccidioidomycosis, United States

被引：103

作者：

Odio, Camila D. ^{[1
,3
]}

Marciano, Beatriz E. ^{[1
]}

Galgiani, John N. ^{[2
]}

Holland, Steven M. ^{[1
]}

机构：

[1] NIH, Bldg 10,Rm 11N248,MSC 1960, Bethesda, MD 20892 USA

[2] Univ Arizona, Coll Med, Tucson, AZ USA

[3] Yale New Haven Med Ctr, 20 York St, New Haven, CT 06504 USA

来源：

EMERGING INFECTIOUS DISEASES | 2017年 / 23卷 / 02期

基金：

美国国家卫生研究院;

关键词：

SIGNAL TRANSDUCER; ACTIVATOR; PULMONARY; PATIENT;

D O I：

10.3201/eid2302.160505

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Of 150,000 new coccidioidomycosis infections that occur annually in the United States, approximate to 1% disseminate; one third of those cases are fatal. Immunocompromised hosts have higher rates of dissemination. We identified 8 patients with disseminated coccidioidomycosis who had defects in the interleukin-12/interferon-gamma and STAT3 axes, indicating that these are critical host defense pathways.

引用

页码：308 / 311

页数：4

共 15 条

[1] Cytokine Profiles from Antigen-Stimulated Whole-Blood Samples among Patients with Pulmonary or Nonmeningeal Disseminated Coccidioidomycosis [J].

Ampel, Neil M. ;

Nesbit, Lance A. ;

Nguyen, Chinh T. ;

Chavez, Suzette ;

Knox, Kenneth S. ;

Johnson, Suzanne M. ;

Pappagianis, Demosthenes .

CLINICAL AND VACCINE IMMUNOLOGY, 2015, 22 (08) :917-922

[2] Factors and Outcomes Associated with the Decision to Treat Primary Pulmonary Coccidioidomycosis [J].

Ampel, Neil M. ;

Giblin, Andrea ;

Mourani, John P. ;

Galgiani, John N. .

CLINICAL INFECTIOUS DISEASES, 2009, 48 (02) :172-178

[3]

[Anonymous], STAT COUNT QUICKFACT

[4] Coccidioidomycosis During Pregnancy: A Review and Recommendations for Management [J].

Bercovitch, Robert S. ;

Catanzaro, Antonino ;

Schwartz, Brian S. ;

Pappagianis, Demosthenes ;

Watts, D. Heather ;

Ampel, Neil M. .

CLINICAL INFECTIOUS DISEASES, 2011, 53 (04) :363-368

[5] Fifteen-year study of the changing epidemiology of methicillin-resistant Staphylococcus aureus [J].

Crum, Nancy F. ;

Lee, Rachel U. ;

Thornton, Scott A. ;

Stine, Colin ;

Wallace, Mark R. ;

Barrozo, Chris ;

Keefer-Norris, Ananda ;

Judd, Sharon ;

Russell, Kevin L. .

AMERICAN JOURNAL OF MEDICINE, 2006, 119 (11) :943-951

[6]

Galgiani JN, 2016, CLIN INFECT DIS, V63, pE112, DOI 10.1093/cid/ciw360

[7] Successful treatment of a critically ill patient with disseminated coccidioidomycosis, using adjunctive interferon-γ [J].

Kuberski, TT ;

Servi, RJ ;

Rubin, PJ .

CLINICAL INFECTIOUS DISEASES, 2004, 38 (06) :910-912

[8] Interleukin-12 regulation of host defenses against Coccidioides immitis [J].

Magee, DM ;

Cox, RA .

INFECTION AND IMMUNITY, 1996, 64 (09) :3609-3613

[9] Effect of Geography on the Analysis of Coccidioidomycosis-Associated Deaths, United states [J].

Noble, Jason A. ;

Nelson, Robert G. ;

Fufaa, Gudeta D. ;

Kang, Paul ;

Shafir, Shira Chani ;

Galgiani, John N. .

EMERGING INFECTIOUS DISEASES, 2016, 22 (10) :1821-1823

[10] COCCIDIOIDES IMMITIS MENINGITIS IN A PATIENT WITH HYPERIMMUNOGLOBULIN E SYNDROME DUE TO A NOVEL MUTATION IN SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION [J].

Powers, Annie E. ;

Bender, Jeffrey M. ;

Kumanovics, Attila ;

Ampofo, Krow ;

Augustine, Nancy ;

Pavia, Andrew T. ;

Hill, Harry R. .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2009, 28 (07) :664-666

← 1 2 →