Infective Endocarditis

被引:341
作者
Hoen, Bruno [1 ,2 ,3 ]
Duval, Xavier [3 ,4 ,5 ]
机构
[1] Univ Franche Comte, Ctr Hosp Reg Univ, Serv Malad Infect & Trop, F-25030 Besancon, France
[2] Univ Franche Comte, CNRS, Unite Mixte Rech Chronoenvironm 6249, F-25030 Besancon, France
[3] Assoc Pour Etude & Prevent Endocardite Infectieus, Paris, France
[4] INSERM, Ctr Invest Clin 007, AP HP, Hop Univ Bichat, Bichat, France
[5] Univ Paris 07, Unite Format & Rech Med Bichat, INSERM, U738, Bichat, France
关键词
CULTURE-NEGATIVE ENDOCARDITIS; STAPHYLOCOCCUS-AUREUS; ANTIPLATELET THERAPY; EMBOLIC EVENTS; CEREBROVASCULAR COMPLICATIONS; ANTIBIOTIC-TREATMENT; VALVE SURGERY; MORTALITY; DIAGNOSIS; GUIDELINES;
D O I
10.1056/NEJMcp1206782
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 55-year-old man with a history of mitral regurgitation seeks care after an episode of transient weakness in his right arm and speech difficulties. He underwent dental scaling 1 month earlier. He notes recent intermittent fevers and weight loss. On cardiac examination, his regurgitation murmur appears to be unchanged. A transthoracic echocardiogram shows a mobile, 12-mm mitral-valve vegetation and grade 2 (mild) regurgitation. Magnetic resonance imaging of the brain reveals recent ischemic lesions. How should the patient be further evaluated and treated?
引用
收藏
页码:1425 / 1433
页数:9
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