Protein trafficking to plastids: one theme, many variations

被引:93
作者
Inaba, Takehito [1 ]
Schnell, Danny J. [1 ,2 ,3 ]
机构
[1] Iwate Univ, 21st Century Ctr Excellence Program, Cryobiofrontier Res Ctr, Morioka, Iwate 0208550, Japan
[2] Univ Massachusetts, Dept Biochem & Mol Biol, Amherst, MA 01003 USA
[3] Univ Massachusetts, Programs Plant & Mol & Cellular Biol, Amherst, MA 01003 USA
关键词
chaperone; chloroplast; plastid; protein import; protein targeting; translocon;
D O I
10.1042/BJ20080490
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Plastids are a diverse group of essential organelles in plants that include chloroplasts. The biogenesis and maintenance of these organelles relies on the import of thousands of nucleus-encoded proteins. The complexity of plastid structure has resulted in the evolution of at least four general import pathways that target proteins into and across the double membrane of the plastid envelope. Several of these pathways can be further divided into specialty pathways that mediate and regulate the import of specific classes of proteins. The co-ordination of import by these specialized pathways with changes in gene expression is critical for plastid and plant development. Moreover, protein import is acutely regulated in response to physiological and metabolic changes within the cell. In the present review we summarize the current knowledge of the mechanism of import via these pathways and highlight the regulatory mechanisms that integrate the plastid protein-trafficking pathways with the developmental and metabolic state of the plant.
引用
收藏
页码:15 / 28
页数:14
相关论文
共 147 条
[1]   Identification of protein transport complexes in the chloroplastic envelope membranes via chemical cross-linking [J].
Akita, M ;
Nielsen, E ;
Keegstra, K .
JOURNAL OF CELL BIOLOGY, 1997, 136 (05) :983-994
[2]   In vivo assessment of the significance of phosphorylation of the Arabidopsis chloroplast protein import receptor, atToc33 [J].
Aronsson, H ;
Combe, J ;
Patel, R ;
Jarvis, P .
FEBS LETTERS, 2006, 580 (02) :649-655
[3]   Toc64/OEP64 is not essential for the efficient import of proteins into chloroplasts in Arabidopsis thaliana [J].
Aronsson, Henrik ;
Boij, Patrik ;
Patel, Ramesh ;
Wardle, Anthony ;
ToPel, Mats ;
Jarvis, Paul .
PLANT JOURNAL, 2007, 52 (01) :53-68
[4]   AKr2A-mediated import of chloroplast outer membrane proteins is essential for chloroplast biogenesis [J].
Bae, Wonsil ;
Lee, Yong Jik ;
Kim, Dae Heon ;
Lee, Junho ;
Kim, Soojin ;
Sohn, Eun Ju ;
Hwang, Inhwan .
NATURE CELL BIOLOGY, 2008, 10 (02) :220-U101
[5]   A molecular-genetic study of the Arabidopsis Toc75 gene family [J].
Baldwin, A ;
Wardle, A ;
Patel, R ;
Dudley, P ;
Park, SK ;
Twell, D ;
Inoue, K ;
Jarvis, P .
PLANT PHYSIOLOGY, 2005, 138 (02) :715-733
[6]  
Bar-Nun S, 2005, CURR TOP MICROBIOL, V300, P95
[7]   The major protein import receptor of plastids is essential for chloroplast biogenesis [J].
Bauer, J ;
Chen, KH ;
Hiltbunner, A ;
Wehrli, E ;
Eugster, M ;
Schnell, D ;
Kessler, F .
NATURE, 2000, 403 (6766) :203-207
[8]   Essential role of the G-domain in targeting of the protein import receptor atToc159 to the chloroplast outer membrane [J].
Bauer, J ;
Hiltbrunner, A ;
Weibel, P ;
Vidi, PA ;
Alvarez-Huerta, M ;
Smith, MD ;
Schnell, DJ ;
Kessler, F .
JOURNAL OF CELL BIOLOGY, 2002, 159 (05) :845-854
[9]   Insertion of bitopic membrane proteins into the inner membrane of mitochondria involves an export step from the matrix [J].
Baumann, F ;
Neupert, W ;
Herrmann, JM .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (24) :21405-21413
[10]   Toc12, a novel subunit of the intermembrane space preprotein translocon of chloroplasts [J].
Becker, T ;
Hritz, J ;
Vogel, M ;
Caliebe, A ;
Bukau, B ;
Soll, J ;
Schleiff, E .
MOLECULAR BIOLOGY OF THE CELL, 2004, 15 (11) :5130-5144