Application of Peak Nasal Inspiratory Flow reference values in the treatment of allergic rhinitis

被引:19
作者
Campos Fernandes, Silvia de Souza [1 ]
De Andrade, Claudia Ribeiro [1 ]
Ibiapina, Cassio da Cunha [1 ]
机构
[1] Univ Fed Minas Gerais, Fac Med, Dept Pediaetr, BR-30130100 Belo Horizonte, MG, Brazil
关键词
rhinitis; flow; score; children; reference values; CHILDREN; ADOLESCENTS; ASTHMA; SYMPTOMS; IMPACT;
D O I
10.4193/Rhino13.158
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Objective: To assess the applicability of the Peak Nasal Inspiratory Flow (PNIF) curves in follow-up of children in the treatment of allergic rhinitis. Methods: Prospective study of 40 patients with AR, grouped in corticosteroid spray versus physiological saline solution use. Follow up for 10 weeks through clinical score and PNIF percentages in relation to the reference curves, with was-out at week 8. Statistical assessment of the effect of treatment on variation of PNIF and clinical score was calculated by ANOVA model and Multiple Comparison of Means Test - Least Significant Difference. Results:There was a statistically significant influence of the group, time and interaction between time and group on PNIF percentages. Throughout follow up, patients from the treatment group had mean PNIF percentages significantly higher than the placebo group. Clinical score results also demonstrated a statistically significant influence between the groups, time and interaction between time and group. Conclusion: Increase in PNIF percentage values observed in children treated with intranasal corticosteroids revealed the applicability of PNIF curves in their follow up.
引用
收藏
页码:133 / 136
页数:4
相关论文
共 19 条
[1]   Global map of the prevalence of symptoms of rhinoconjunctivitis in children: The International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three [J].
Ait-Khaled, N. ;
Pearce, N. ;
Anderson, H. R. ;
Ellwood, P. ;
Montefort, S. ;
Shah, J. .
ALLERGY, 2009, 64 (01) :123-148
[2]   Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood:: ISAAC Phases One and Three repeat multicountry cross-sectional surveys [J].
Asher, M. Innes ;
Montefort, Stephen ;
Bjorksten, Bengt ;
Lai, Christopher K. W. ;
Strachan, David P. ;
Weiland, Stephan K. ;
Williams, Hywel .
LANCET, 2006, 368 (9537) :733-743
[3]   Allergic Rhinitis and its Impact on Asthma (ARIA): Achievements in 10 years and future needs [J].
Bousquet, J. ;
Schuenemann, H. J. ;
Samolinski, B. ;
Demoly, P. ;
Baena-Cagnani, C. E. ;
Bachert, C. ;
Bonini, S. ;
Boulet, L. P. ;
Bousquet, P. J. ;
Brozek, J. L. ;
Canonica, G. W. ;
Casale, T. B. ;
Cruz, A. A. ;
Fokkens, W. J. ;
Fonseca, J. A. ;
van Wijk, R. Gerth ;
Grouse, L. ;
Haahtela, T. ;
Khaltaev, N. ;
Kuna, P. ;
Lockey, R. F. ;
Carlsen, K. C. Lodrup ;
Mullol, J. ;
Naclerio, R. ;
O'Hehir, R. E. ;
Ohta, K. ;
Palkonen, S. ;
Papadopoulos, N. G. ;
Passalacqua, G. ;
Pawankar, R. ;
Price, D. ;
Ryan, D. ;
Simons, F. E. R. ;
Togias, A. ;
Williams, D. ;
Yorgancioglu, A. ;
Yusuf, O. M. ;
Aberer, W. ;
Adachi, M. ;
Agache, I. ;
Ait-Khaled, N. ;
Akdis, C. A. ;
Andrianarisoa, A. ;
Annesi-Maesano, I. ;
Ansotegui, I. J. ;
Baiardini, I. ;
Bateman, E. D. ;
Bedbrook, A. ;
Beghe, B. ;
Beji, M. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2012, 130 (05) :1049-1062
[4]   Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 Revision [J].
Brozek, Jan L. ;
Bousquet, Jean ;
Baena-Cagnani, Carlos E. ;
Bonini, Sergio ;
Canonica, G. Walter ;
Casale, Thomas B. ;
van Wijk, Roy Gerth ;
Ohta, Ken ;
Zuberbier, Torsten ;
Schuenemann, Holger J. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2010, 126 (03) :466-476
[5]  
Chaves C, 2012, RHINOLOGY, V50, P381, DOI [10.4193/Rhin12.073, 10.4193/Rhino12.073]
[6]  
Dor-Wojnarowska Anna, 2011, Pneumonol Alergol Pol, V79, P320
[7]  
Gomes DD, 2008, RHINOLOGY, V46, P276
[8]   Reference values for peak nasal inspiratory flow in children and adolescents in Brazil [J].
Ibiapina, Cassio da Cunha ;
de Andrade, Claudia Ribeiro ;
Moreira Camargos, Paulo Augusto ;
Alvim, Cristina Goncalves ;
Cruz, Alvaro Augusto .
RHINOLOGY, 2011, 49 (03) :304-308
[9]   As-needed use of fluticasone propionate nasal spray reduces symptoms of seasonal allergic rhinitis [J].
Jen, A ;
Baroody, F ;
deTineo, M ;
Haney, L ;
Blair, C ;
Naclerio, R .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2000, 105 (04) :732-738
[10]   Prevalence of symptoms of asthma, rhinitis and atopic eczema among students between 6 and 7 years of age in the city of Londrina, Brazil [J].
Kuromoto de Castro, Luci Keiko ;
Cerci Neto, Alcindo ;
Ferreira Filho, Olavo Franco .
JORNAL BRASILEIRO DE PNEUMOLOGIA, 2010, 36 (03) :286-292